Survey of tick-borne zoonotic viruses in wild deer in Hokkaido, Japan

Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS phlebovirus (SFTSV). In 2016, a second domestic TBE case was reported in Hokkaido, Japan, after an absence of 23 years. We conducted IgG ELIS...

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Published inJournal of Veterinary Medical Science Vol. 80; no. 6; pp. 985 - 988
Main Authors UCHIDA, Leo, HAYASAKA, Daisuke, TUN, Mya Myat NGWE, MORITA, Kouichi, MURAMATSU, Yasukazu, HAGIWARA, Katsuro
Format Journal Article
LanguageEnglish
Published Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2018
The Japanese Society of Veterinary Science
Subjects
Animals
Deer - parasitology
Encephalitis Viruses, Tick-Borne - isolation & purification
Encephalitis, Tick-Borne - epidemiology
Encephalitis, Tick-Borne - veterinary
Female
Japan - epidemiology
Male
Public Health
serosurvey
severe fever with thrombocytopenia syndrome virus
Surveys and Questionnaires
tick-borne encephalitis virus
wild deer
zoonotic disease
Japan
serosurvey
wild deer
zoonotic disease
severe fever with thrombocytopenia syndrome virus
tick-borne encephalitis virus
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Abstract Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS phlebovirus (SFTSV). In 2016, a second domestic TBE case was reported in Hokkaido, Japan, after an absence of 23 years. We conducted IgG ELISA for TBEV and SFTSV on 314 deer (Cervus nippon yesoensis) serum samples collected from 3 places in Hokkaido. There were 7 seropositive samples for TBEV but none for SFTSV by ELISA. The specificity of the 7 positive samples was confirmed by neutralization tests against TBEV, and 5 sera showed 320 to 640 of 50% focus reduction endpoint titers. Our results provide information about the infectious status of TBEV in wild deer in Hokkaido, Japan.
AbstractList Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS phlebovirus (SFTSV). In 2016, a second domestic TBE case was reported in Hokkaido, Japan, after an absence of 23 years. We conducted IgG ELISA for TBEV and SFTSV on 314 deer ( Cervus nippon yesoensis ) serum samples collected from 3 places in Hokkaido. There were 7 seropositive samples for TBEV but none for SFTSV by ELISA. The specificity of the 7 positive samples was confirmed by neutralization tests against TBEV, and 5 sera showed 320 to 640 of 50% focus reduction endpoint titers. Our results provide information about the infectious status of TBEV in wild deer in Hokkaido, Japan.
Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS phlebovirus (SFTSV). In 2016, a second domestic TBE case was reported in Hokkaido, Japan, after an absence of 23 years. We conducted IgG ELISA for TBEV and SFTSV on 314 deer (Cervus nippon yesoensis) serum samples collected from 3 places in Hokkaido. There were 7 seropositive samples for TBEV but none for SFTSV by ELISA. The specificity of the 7 positive samples was confirmed by neutralization tests against TBEV, and 5 sera showed 320 to 640 of 50% focus reduction endpoint titers. Our results provide information about the infectious status of TBEV in wild deer in Hokkaido, Japan.
Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS phlebovirus (SFTSV). In 2016, a second domestic TBE case was reported in Hokkaido, Japan, after an absence of 23 years. We conducted IgG ELISA for TBEV and SFTSV on 314 deer (Cervus nippon yesoensis) serum samples collected from 3 places in Hokkaido. There were 7 seropositive samples for TBEV but none for SFTSV by ELISA. The specificity of the 7 positive samples was confirmed by neutralization tests against TBEV, and 5 sera showed 320 to 640 of 50% focus reduction endpoint titers. Our results provide information about the infectious status of TBEV in wild deer in Hokkaido, Japan.Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS phlebovirus (SFTSV). In 2016, a second domestic TBE case was reported in Hokkaido, Japan, after an absence of 23 years. We conducted IgG ELISA for TBEV and SFTSV on 314 deer (Cervus nippon yesoensis) serum samples collected from 3 places in Hokkaido. There were 7 seropositive samples for TBEV but none for SFTSV by ELISA. The specificity of the 7 positive samples was confirmed by neutralization tests against TBEV, and 5 sera showed 320 to 640 of 50% focus reduction endpoint titers. Our results provide information about the infectious status of TBEV in wild deer in Hokkaido, Japan.
Author TUN, Mya Myat NGWE
HAGIWARA, Katsuro
MORITA, Kouichi
MURAMATSU, Yasukazu
UCHIDA, Leo
HAYASAKA, Daisuke
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  fullname: HAYASAKA, Daisuke
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  fullname: TUN, Mya Myat NGWE
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  organization: Department of Virology, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki 852-8523, Japan
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  organization: Laboratory of Veterinary Virology, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyodai-Midorimachi, Ebetsu, Hokkaido 069-8501, Japan
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Keywords serosurvey
wild deer
zoonotic disease
severe fever with thrombocytopenia syndrome virus
tick-borne encephalitis virus
Language English
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– reference: 17. Skarphédinsson, S., Jensen, P. M. and Kristiansen, K. 2005. Survey of tickborne infections in Denmark. Emerg. Infect. Dis. 11: 1055–1061.
– reference: 20. Takeda, T., Ito, T., Chiba, M., Takahashi, K., Niioka, T. and Takashima, I. 1998. Isolation of tick-borne encephalitis virus from Ixodes ovatus (Acari: Ixodidae) in Japan. J. Med. Entomol. 35: 227–231.
– reference: 7. Infectious, A. S. R. 2016. https://www0.niid.go.jp/niid/idsc/iasr/37/433j.pdf [accessed on May 18 2018] (in Japanese).
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– reference: 4. Hubálek, Z. and Rudolf, I. 2012. Tick-borne viruses in Europe. Parasitol. Res. 111: 9–36.
– reference: 18. Takamatsu, Y., Okamoto, K., Dinh, D. T., Yu, F., Hayasaka, D., Uchida, L., Nabeshima, T., Buerano, C. C. and Morita, K. 2014. NS1′ protein expression facilitates production of Japanese encephalitis virus in avian cells and embryonated chicken eggs. J. Gen. Virol. 95: 373–383.
– reference: 5. Igota, H., Sakuragi, M., Uno, H., Kaji, K., Kaneko, M., Akamatsu, R. and Maekawa, K. 2004. Seasonal migration patterns of female sika deer in eastern Hokkaido, Japan. Ecol. Res. 19: 169–178.
– reference: 13. Knap, N. and Avšič-Županc, T. 2013. Correlation of TBE incidence with red deer and roe deer abundance in Slovenia. PLoS One 8: e66380.
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Snippet Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS...
Tick-borne encephalitis (TBE) and severe fever with thrombocytopenia syndrome (SFTS) are both tick-borne zoonotic diseases caused by TBE virus (TBEV) and SFTS...
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SubjectTerms Animals
Deer - parasitology
Encephalitis Viruses, Tick-Borne - isolation & purification
Encephalitis, Tick-Borne - epidemiology
Encephalitis, Tick-Borne - veterinary
Female
Japan - epidemiology
Male
Public Health
serosurvey
severe fever with thrombocytopenia syndrome virus
Surveys and Questionnaires
tick-borne encephalitis virus
wild deer
zoonotic disease
Title Survey of tick-borne zoonotic viruses in wild deer in Hokkaido, Japan
URI https://www.jstage.jst.go.jp/article/jvms/80/6/80_18-0017/_article/-char/en
https://www.ncbi.nlm.nih.gov/pubmed/29669948
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https://pubmed.ncbi.nlm.nih.gov/PMC6021891
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