Modulation of microbially derived short-chain fatty acids on intestinal homeostasis, metabolism, and neuropsychiatric disorder

• Published in: Applied microbiology and biotechnology Vol. 104; no. 2; pp. 589 - 601
• Main Authors: Xiao, Suwei, Jiang, Shu, Qian, Dawei, Duan, Jinao
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2020; Springer; Springer Nature B.V
• Subjects: Bacteria; bacterial proteins; Bile; Bile acids; Biomedical and Life Sciences; Biotechnology; Cholesterol; Colon; Dietary fiber; Digestive system; Fatty acids; Fermentation; Gastrointestinal tract; harvesting; Homeostasis; Intermediates; Intestinal microflora; intestinal microorganisms; Intestine; inventories; Life Sciences; Mental disorders; Metabolism; Metabolites; microbial communities; Microbial Genetics and Genomics; Microbiology; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Mini-Review; Nervous system diseases; Neuroprotection; neuroprotective effect; Nutrients; pathophysiology; Physiological aspects; short chain fatty acids; Type 2 diabetes; Vitamins; Host health; Short-chain fatty acids; Microbiota; Dietary carbohydrates

A diverse range of symbiotic gut bacteria codevelops with the host and is considered a metabolic “organ” that not only facilitates harvesting of nutrients from the dietary components but also produces a class of metabolites. Many metabolites of gut microbes have an important impact on host health. F...