Robust tumor immunity to melanoma mediated by interleukin-9–producing T cells - Purwar, Rahul; Schlapbach, Christoph; Xiao, Sheng; Kang, Hong Soon; Elyaman, Wassim; Jiang, Xiaodong; Jetten, Anton M; Khoury, Samia J; Fuhlbrigge, Robert C; Kuchroo, Vijay K; Clark, Rachael A; Kupper, Thomas S (Nature medicine, 2012)
Keywords: 631/250/127/1213; 692/699/67/1813/1634; 692/699/67/580; Allergies; Animals; Biomedical and Life Sciences; Biomedicine; Blood; Cancer Research; Cancer Vaccines; Carcinoma, Lewis Lung - immunology; Carcinoma, Lewis Lung - pathology; Care and treatment; Cellular immunity; Cytokines; Diagnosis; Disease Progression; Gene expression; Gene Expression Profiling; Genetic aspects; Health aspects; Homeodomain Proteins - genetics; Humans; Immune system; Immunotherapy, Adoptive; Infectious Diseases; Interleukin-9; Interleukin-9 - analysis; Interleukin-9 - biosynthesis; Interleukin-9 - genetics; Interleukin-9 - physiology; Lesions; Lymphatic Metastasis; Lymphocytes; Lymphocytes, Tumor-Infiltrating - immunology; Mast Cells - drug effects; Mast Cells - immunology; Melanoma; Melanoma - chemistry; Melanoma - immunology; Melanoma - pathology; Melanoma - secondary; Melanoma, Experimental - immunology; Melanoma, Experimental - pathology; Melanoma, Experimental - therapy; Metabolic Diseases; Metastasis; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Medicine; Neoplasm Proteins - analysis; Neoplasm Proteins - biosynthesis; Neoplasm Proteins - genetics; Neoplasm Proteins - physiology; Neurosciences; Nuclear Receptor Subfamily 1, Group F, Member 3 - deficiency; Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics; Radiation Chimera; Receptors, Interleukin - deficiency; Receptors, Interleukin - genetics; Recombinant Fusion Proteins - physiology; Skin - immunology; Skin cancer; Skin Neoplasms - chemistry; Skin Neoplasms - immunology; Skin Neoplasms - pathology; T cells; T-Lymphocyte Subsets - immunology; T-Lymphocyte Subsets - metabolism; Tumor Burden; Tumors; Vaccination; United States