Osmotic diuresis by SGLT2 inhibition stimulates vasopressin‐induced water reabsorption to maintain body fluid volume - Masuda, Takahiro; Muto, Shigeaki; Fukuda, Keiko; Watanabe, Minami; Ohara, Ken; Koepsell, Hermann; Vallon, Volker; Nagata, Daisuke (Physiological reports, 2020)
Keywords: Animals; Aquaporin 1; Aquaporin 2; Aquaporins; bioimpedance analysis; Blood pressure; Body Fluid Compartments - drug effects; Body Fluid Compartments - metabolism; Body Fluids - drug effects; Body Fluids - metabolism; Body weight; Diabetes; Diabetes mellitus; Diuresis; Diuresis - drug effects; Diuresis - physiology; Diuretics; Diuretics, Osmotic - pharmacology; Electrolytes; Fluid intake; Food; Food intake; Glucose transporter; Glucosides - pharmacology; glucosuria; Heart failure; Kidneys; Membrane proteins; Metabolism and Regulation; Na+/glucose cotransporter; Original Research; Osmosis - drug effects; Osmosis - physiology; Physiology; Rats; Reabsorption; Renal function; Renal Physiology; Renal Reabsorption - drug effects; Renal Reabsorption - physiology; Renal tubules; SGLT2 inhibition; Sodium; Sodium-Glucose Transporter 2 Inhibitors - pharmacology; Spectroscopy; Thiophenes - pharmacology; Urine; Vasopressin; Vasopressins - urine; Water - metabolism; water reabsorption; Japan; water reabsorption; bioimpedance analysis; SGLT2 inhibition; vasopressin; glucosuria