Pharmacogenetic Randomized Trial for Cocaine Abuse: Disulfiram and Dopamine β-Hydroxylase - Kosten, Thomas R.; Wu, Guiying; Huang, Wen; Harding, Mark J.; Hamon, Sara C.; Lappalainen, Jaakko; Nielsen, David A. (Biological psychiatry (1969), 2013)
Keywords: Addictive behaviors; Adult; Adult and adolescent clinical studies; Biological and medical sciences; Cocaine; Cocaine-Related Disorders - complications; Cocaine-Related Disorders - drug therapy; Cocaine-Related Disorders - genetics; dependence; disulfiram; Disulfiram - therapeutic use; Dopamine beta-Hydroxylase - genetics; Drug addiction; Drug Therapy, Combination; Female; genes; Genotype; Humans; Male; Medical sciences; Methadone - therapeutic use; Middle Aged; Opioid-Related Disorders - complications; Opioid-Related Disorders - drug therapy; Opioid-Related Disorders - genetics; polymorphism; Polymorphism, Single Nucleotide; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; treatment; Treatment Outcome; treatment; dependence; Cocaine; disulfiram; polymorphism; genes; Dopamine β-monooxygenase; Drug addiction; Pharmacogenetics; Antialcohol drug; Enzyme; Genetic determinism; Ester; Treatment; Gene; Dependence; Disulfiram; Genetics; Drug of abuse; Oxidoreductases; Polymorphism