Cathelicidin Antimicrobial Peptide LL-37 in Psoriasis Enables Keratinocyte Reactivity against TLR9 Ligands
Here we show that keratinocytes in psoriatic lesional skin express increased Toll-like receptor (TLR) 9 that similarly localizes with elevated expression of the cathelicidin antimicrobial peptide LL-37. In culture, normal human keratinocytes exposed to LL-37 increased TLR9 expression. Furthermore, w...
Saved in:
Published in | Journal of investigative dermatology Vol. 132; no. 1; pp. 135 - 143 |
---|---|
Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.01.2012
Nature Publishing Group Elsevier Limited |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!