A glance on the role of fibronectin in controlling cell response at biomaterial interface

• Published in: The Japanese dental science review Vol. 56; no. 1; pp. 50 - 55
• Main Authors: Parisi, Ludovica, Toffoli, Andrea, Ghezzi, Benedetta, Mozzoni, Beatrice, Lumetti, Simone, Macaluso, Guido M.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.11.2020; Elsevier
• Subjects: Biomaterials; Bone regeneration; Fibronectin; Regenerative medicine; Tissue engineering; Tissue engineering; Regenerative medicine; Bone regeneration; Fibronectin; Biomaterials

The bioactivity of biomaterials is closely related to cell response in contact with them. However, shortly after their insertion, materials are soon covered with proteins that constitute the biological fluids, and which render the direct surface recognition by cells almost impossible. The control of...