The role of three calcineurin subunits and a related transcription factor (Crz1) in conidiation, multistress tolerance and virulence in Beauveria bassiana

• Published in: Applied microbiology and biotechnology Vol. 99; no. 2; pp. 827 - 840
• Main Authors: Li, Fang, Wang, Zheng-Liang, Zhang, Long-Bin, Ying, Sheng-Hua, Feng, Ming-Guang
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2015; Springer; Springer Nature B.V
• Subjects: Agricultural chemicals; Animals; Applied Genetics and Molecular Biotechnology; Ascomycota; Beauveria - genetics; Beauveria - pathogenicity; Beauveria - physiology; Beauveria bassiana; Biological Control Agents; Biomedical and Life Sciences; Biotechnology; Calcineurin; Calcineurin - chemistry; Calcineurin - genetics; Catalase - metabolism; Cell cycle; Cell Wall - metabolism; Cloning, Molecular; Down-Regulation; Environmental stress; Escherichia coli - genetics; Fungal Proteins - chemistry; Fungal Proteins - genetics; Fungi; Fungicides; Gene Deletion; Gene expression; Genes; Genetic aspects; Health aspects; Insecticides; Irradiation; Kinases; Larva; Larvae; Lethal Dose 50; Life Sciences; Microbial Genetics and Genomics; Microbiology; Morphology; Oxidizing agents; Phenotype; Phosphatase; Phosphorylation; Proteins; Spodoptera - microbiology; Spodoptera litura; Stress, Physiological; Studies; Superoxide Dismutase - metabolism; Transcription factors; Transcription Factors - chemistry; Transcription Factors - genetics; Virulence; Virulence (Microbiology); Yeast; Calcineurin pathway; Asexual development; Entomopathogenic fungi; Stress response; Virulence; Functional diversity

The eukaryotic calcineurin (CN) pathway comprising catalytic A (CnA) and regulatory B subunits (CnB) is crucial for many biological processes but functionally unexplored in entomopathogenic fungi. Here, we characterise three CN subunits (CnA1, CnA2 and CnB) and a downstream CN-responsive zinc finger...