Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes - Lee, Hye-Mi; Kim, Jwa-Jin; Kim, Hyun Jin; Shong, Minho; Ku, Bon Jeong; Jo, Eun-Kyeong (Diabetes (New York, N.Y.), 2013)
Keywords: Adult; Aged; AMP-Activated Protein Kinases - physiology; Antidiabetics; Apoptosis; Biological and medical sciences; CARD Signaling Adaptor Proteins; Care and treatment; Carrier Proteins - genetics; Carrier Proteins - physiology; Cytokines; Cytoskeletal Proteins - genetics; Diabetes; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - metabolism; Diabetes. Impaired glucose tolerance; Diagnosis; Dosage and administration; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Fatty acids; Female; Glucose; Homeostasis; Humans; Immunology and Transplantation; Inflammasomes - physiology; Inflammation; Insulin resistance; Interleukin-1; Interleukin-18 - biosynthesis; Interleukin-1beta - biosynthesis; Interleukin-1beta - genetics; Kinases; Male; Medical sciences; Metformin; Metformin - therapeutic use; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Obesity; Pathogenesis; Polypeptides; Protein expression; Proteins; Reactive Oxygen Species - metabolism; RNA, Messenger - analysis; Type 2 diabetes; Uric acid; South Korea; Endocrinopathy; Type 2 diabetes; Human; Metabolic diseases