A Genomic Perspective on the Origin and Emergence of SARS-CoV-2

• Published in: Cell Vol. 181; no. 2; pp. 223 - 227
• Main Authors: Zhang, Yong-Zhen, Holmes, Edward C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 16.04.2020
• Subjects: animal viruses; Animals; Animals, Wild; Betacoronavirus - genetics; China; Chiroptera - virology; Coronavirus Infections - transmission; Coronavirus Infections - virology; COVID-19; Disease Reservoirs - virology; DNA, Environmental; Genome, Viral; genomics; pandemic; Pandemics; Pneumonia, Viral - transmission; Pneumonia, Viral - virology; SARS-CoV-2; sequence analysis; Sequence Analysis, RNA; viruses; Zoonoses - virology; China

The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understandin...