A Genomic Perspective on the Origin and Emergence of SARS-CoV-2

The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understandin...

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Published inCell Vol. 181; no. 2; pp. 223 - 227
Main Authors Zhang, Yong-Zhen, Holmes, Edward C.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 16.04.2020
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Abstract The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understanding of its origins.
AbstractList The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understanding of its origins.The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understanding of its origins.
The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understanding of its origins.
Author Holmes, Edward C.
Zhang, Yong-Zhen
Author_xml – sequence: 1
  givenname: Yong-Zhen
  surname: Zhang
  fullname: Zhang, Yong-Zhen
  organization: Shanghai Public Health Clinical Center and School of Life Science, Fudan University, Shanghai, China
– sequence: 2
  givenname: Edward C.
  surname: Holmes
  fullname: Holmes, Edward C.
  email: edward.holmes@sydney.edu.au
  organization: Shanghai Public Health Clinical Center and School of Life Science, Fudan University, Shanghai, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32220310$$D View this record in MEDLINE/PubMed
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Snippet The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome...
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SubjectTerms animal viruses
Animals
Animals, Wild
Betacoronavirus - genetics
China
Chiroptera - virology
Coronavirus Infections - transmission
Coronavirus Infections - virology
COVID-19
Disease Reservoirs - virology
DNA, Environmental
Genome, Viral
genomics
pandemic
Pandemics
Pneumonia, Viral - transmission
Pneumonia, Viral - virology
SARS-CoV-2
sequence analysis
Sequence Analysis, RNA
viruses
Zoonoses - virology
Title A Genomic Perspective on the Origin and Emergence of SARS-CoV-2
URI https://dx.doi.org/10.1016/j.cell.2020.03.035
https://www.ncbi.nlm.nih.gov/pubmed/32220310
https://www.proquest.com/docview/2384216150
https://www.proquest.com/docview/2439393517
https://pubmed.ncbi.nlm.nih.gov/PMC7194821
Volume 181
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