Favorable Outcome Following Sotrovimab Monoclonal Antibody in a Patient with Prolonged SARS-CoV-2 Omicron Infection with HIV/AIDS

• Published in: Internal Medicine Vol. 61; no. 22; pp. 3459 - 3462
• Main Authors: Adachi, Eisuke, Koga, Michiko, Yotsuyanagi, Hiroshi, Tsutsumi, Takeya, Saito, Makoto
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 15.11.2022; Japan Science and Technology Agency
• Subjects: Acquired immune deficiency syndrome; Acquired Immunodeficiency Syndrome; AIDS; Antibodies, Monoclonal - therapeutic use; Antibodies, Viral; Case Report; Coronaviruses; COVID-19; COVID-19 - complications; COVID-19 Drug Treatment; HIV; HIV/AIDS; Human immunodeficiency virus; Humans; Immune reconstitution; Immunodeficiency; Immunotherapy; Inflammation; Internal medicine; Monoclonal antibodies; monoclonal antibody therapy; passive immunity; Patients; persistent viral shedding; prolonged COVID-19; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; sotrovimab; HIV/AIDS; prolonged COVID-19; passive immunity; sotrovimab; monoclonal antibody therapy; persistent viral shedding

Persistent viral shedding or prolonged coronavirus disease 2019 (COVID-19) symptom is one of unresolved problem in immunocompromised individuals. We herein report an HIV/AIDS patient with Pneumocystis jirovecii pneumonia and prolonged COVID-19, possibly due to immune reconstitution inflammatory synd...