A Randomized Controlled Trial of Trypsin to Treat Brown Recluse Spider Bites in Guinea Pigs - Cabaniss, Wyman W.; Bush, Sean; O’Rourke, Dorcas P.; Fletcher, Paul F.; Brewer, Kori L.; Lertpiriyapong, Kvin; Punja, Mohan; Miller, Susan N.; Meggs, William J. (Journal of medical toxicology, 2014)
Keywords: Analgesia; Anesthesia; Animals; Antidotes; Biomedical and Life Sciences; Biomedicine; Bites; Brown Recluse Spider; Buprenorphine; Enzymes; Female; Guinea Pigs; Insect bites; Isoflurane; Lesions; Pain perception; Pharmacology/Toxicology; Placebo effect; Proteolysis; Randomization; Rodents; Skin diseases; Skin lesions; Spider Bites - drug therapy; Spiders; Statistical analysis; Toxicity; Toxicology Investigation; Toxins; Trypsin; Trypsin - therapeutic use; Variance analysis; Venom; Venom toxins; Spider bites; Trypsin