Deciphering next-generation pharmacogenomics: an information technology perspective

• Published in: Open biology Vol. 4; no. 7; p. 140071
• Main Authors: Potamias, George, Lakiotaki, Kleanthi, Katsila, Theodora, Lee, Ming Ta Michael, Topouzis, Stavros, Cooper, David N., Patrinos, George P.
• Format: Journal Article
• Language: English
• Published: England The Royal Society 01.07.2014
• Subjects: Drug Metabolism; Gene Variants; Genome; Genomics - methods; High-Throughput Nucleotide Sequencing - methods; Humans; Informatics Solutions; Microattribution; Personalized Pharmacogenomics Profile; Perspective; Pharmacogenetics - methods; Precision Medicine - methods; Whole-Genome Sequencing; personalized pharmacogenomics profile; informatics solutions; microattribution; gene variants; whole-genome sequencing; drug metabolism

In the post-genomic era, the rapid evolution of high-throughput genotyping technologies and the increased pace of production of genetic research data are continually prompting the development of appropriate informatics tools, systems and databases as we attempt to cope with the flood of incoming gen...