RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5 - Du, Xian; Qin, Wenying; Yang, Chunyu; Dai, Lin; San, Mingkui; Xia, Yingdan; Zhou, Siyu; Wang, Mengyang; Wu, Shuang; Zhang, Shaorui; Zhou, Huiting; Li, Fangshu; et al. (Genome Biology, 2024)
Keywords: 5′ pausing; Chromatin; DNA-directed RNA polymerase; Elongation; Gene expression; genes; Genomes; Homeostasis; Humans; loci; Molecular modelling; Positive Transcriptional Elongation Factor B - genetics; Positive Transcriptional Elongation Factor B - metabolism; Proteins; RBM22; RNA; RNA polymerase; RNA polymerase II; RNA Polymerase II - metabolism; RNA Splicing; RNA Splicing Factors - genetics; Splicing factors; transcription (genetics); Transcription elongation; Transcription termination; Transcription, Genetic; Transcriptional Elongation Factors - genetics; Transcriptional Elongation Factors - metabolism; Transcription termination; Transcription elongation; 5′ pausing; RNA polymerase II; RBM22