Multidrug-resistant Acinetobacter baumannii : mechanisms of virulence and resistance

• Published in: International journal of antimicrobial agents Vol. 35; no. 3; pp. 219 - 226
• Main Authors: Gordon, Nicola C, Wareham, David W
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.03.2010; Elsevier
• Subjects: Acinetobacter baumannii; Acinetobacter baumannii - drug effects; Acinetobacter baumannii - pathogenicity; Acinetobacter Infections - drug therapy; Acinetobacter Infections - microbiology; Anti-Bacterial Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobial resistance; Bacterial Proteins - physiology; Biological and medical sciences; Drug Resistance, Multiple, Bacterial; Humans; Infectious Disease; Medical sciences; Pathogenesis; Pharmacology. Drug treatments; Virulence; Virulence Factors - physiology; Pathogenesis; Acinetobacter baumannii; Antimicrobial resistance; Drug susceptibility test; Multiple resistance; Virulence; Neisseriaceae; Bacteria; Micrococcales; Mechanism of action; Antimicrobial agent

Abstract Infection due to Acinetobacter baumannii has become a significant challenge to modern healthcare systems. The organism shows a formidable capacity to develop antimicrobial resistance, yet the clinical impact of A. baumannii infection remains unclear. Much is known about the processes involv...