Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation - McCallum, Matthew; Walls, Alexandra C.; Bowen, John E.; Corti, Davide; Veesler, David (Nature structural & molecular biology, 2020)
Keywords: 101/28; 631/326/596/4130; 631/535/1258/1259; Antibodies, Monoclonal - metabolism; Antibodies, Neutralizing - metabolism; Betacoronavirus - chemistry; Betacoronavirus - genetics; Betacoronavirus - immunology; Betacoronavirus - metabolism; Biochemistry; Biological Microscopy; Biomedical and Life Sciences; Causes of; Conformation; Coronaviruses; Cryoelectron Microscopy; Disulfides - chemistry; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epidemics; Genetic aspects; Glycoproteins; Health aspects; Humans; Life Sciences; Membrane Biology; Models, Molecular; Mutation; Properties; Protein Conformation; Protein Domains; Protein Engineering; Protein Multimerization; Protein Stability; Protein Structure; Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Spike Glycoprotein, Coronavirus - metabolism; United States; Virulence (Microbiology); United States