The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy

• Published in: Nature reviews cardiology Vol. 18; no. 8; pp. 565 - 580
• Main Authors: Ricard, Nicolas, Bailly, Sabine, Guignabert, Christophe, Simons, Michael
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.08.2021
• Subjects: Endothelium; Endothelium - physiology; Humans; Signal Transduction

Endothelial cells are at the interface between circulating blood and tissues. This position confers on them a crucial role in controlling oxygen and nutrient exchange and cellular trafficking between blood and the perfused organs. The endothelium adopts a structure that is specific to the needs and...