Multi-elemental bio-imaging of rat tissue from a study investigating the bioavailability of bismuth from shotgun pellets

• Published in: Analytical and bioanalytical chemistry Vol. 404; no. 1; pp. 89 - 99
• Main Authors: Urgast, Dagmar S., Ellingsen, Dag G., Berlinger, Balázs, Eilertsen, Einar, Friisk, Grete, Skaug, Vidar, Thomassen, Yngvar, Beattie, John H., Kwun, In-Sook, Feldmann, Jörg
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.07.2012; Springer
• Subjects: Ablation; Ablation (Surgery); Analytical Chemistry; Animals; Bioavailability; Biochemistry; Biological Availability; Bismuth; Bismuth - analysis; Bismuth - pharmacokinetics; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Firearms; Food Science; Humans; Implants; Investigations; Laboratory Medicine; Laser ablation; Laser Therapy - instrumentation; Laser Therapy - methods; Male; Mass Spectrometry - instrumentation; Mass Spectrometry - methods; Mathematical analysis; Molecular Imaging - methods; Monitoring/Environmental Analysis; Original Paper; Pellets; Rats; Rats, Wistar; Wounds, Gunshot - diagnosis; Wounds, Gunshot - metabolism; Zinc; Bismuth; LA-ICP-MS; Rat; Tissue thin section; Bio-imaging

In recent years, bismuth has been promoted as a “green element” and is used as a substitute for the toxic lead in ammunition and other applications. However, the bioavailability and toxicity of bismuth is still not very well described. Following a hunting accident with bismuth-containing shots, a bi...