Macrovascular Complications and Prevalence of Urgency Incontinence in Japanese Patients with Type 2 Diabetes Mellitus: The Dogo Study

• Published in: Internal Medicine Vol. 56; no. 8; pp. 889 - 893
• Main Authors: Tanaka, Keiko, Ueda, Teruhisa, Hiasa, Yoichi, Senba, Hidenori, Yamamoto, Shin, Matsuura, Bunzo, Maruyama, Koutatsu, Tanigawa, Takeshi, Furukawa, Shinya, Miyake, Yoshihiro, Torisu, Masamoto, Kanzaki, Sayaka, Miyaoka, Hiroaki, Minami, Hisaka, Sakai, Takenori, Niiya, Tetsuji, Miyake, Teruki, Onji, Morikazu
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.01.2017; Japan Science and Technology Agency
• Subjects: Adult; Aged; Aged, 80 and over; Body mass index; Coronary artery disease; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetic Nephropathies - epidemiology; Diabetic Neuropathies - epidemiology; Diabetic retinopathy; Diabetic Retinopathy - epidemiology; Dyslipidemia; Dyslipidemias - complications; Female; Glycated Hemoglobin A; Health risk assessment; Heart diseases; Hemoglobin; Humans; Hypertension - complications; incontinence; Internal medicine; Ischemia; Japanese; macrovascular complications; Male; Middle Aged; Myocardial Ischemia - epidemiology; Nephropathy; Odds Ratio; Original; Peripheral neuropathy; Prevalence; Retinopathy; Risk Factors; Smoking; Stroke; Stroke - epidemiology; Urinary Incontinence, Urge - epidemiology; Urinary Incontinence, Urge - etiology; Urine; Vascular diseases; Young Adult; incontinence; macrovascular complications; Japanese; diabetes; stroke
• ISSN: 0918-2918; 1349-7235; 1349-7235
• DOI: 10.2169/internalmedicine.56.8063

Objective Macrovascular diseases and urgency incontinence are common among Japanese patients with type 2 diabetes mellitus. However, little evidence exists regarding the association between stroke and urgency incontinence among patients with type 2 diabetes mellitus. We examined the associations between macrovascular complications and urgency incontinence among Japanese patients with type 2 diabetes mellitus. Methods The study subjects were 818 Japanese patients with type 2 diabetes mellitus. Urgency incontinence was defined as present when a subject answered "once a week or more" to the question: "Within one week, how often do you leak urine because you cannot defer the sudden desire to urinate?" We adjusted our analyses for sex, age, body mass index, duration of type 2 diabetes, current smoking, current drinking, hypertension, dyslipidemia, glycated hemoglobin, diabetic nephropathy, diabetic retinopathy, and diabetic peripheral neuropathy. Results The prevalence of urgency incontinence was 9.2%. Stroke was independently positively associated with urgency incontinence, with an adjusted odds ratio of 2.34 (95% confidence interval: 1.03-4.95). The associations between ischemic heart disease or peripheral artery disease and the prevalence of urgency incontinence were not significant. Conclusion In Japanese patients with type 2 diabetes mellitus, stroke, but not ischemic heart diseases or peripheral artery disease, was independently positively associated with urgency incontinence.