Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors - Maenaka, Katsumi; Kojima, Hirotatsu; Nomura, Takao; Suzuki, Tateki; Sawa, Hirofumi; Hasegawa, Tsukasa; Otsuguro, Satoko; Orba, Yasuko; Nagano, Tetsuo; Sasaki, Michihito; Hashiguchi, Takao; Sato, Akihiko; et al. (Chemical & pharmaceutical bulletin, 2022)
Keywords: acoustic ejection MS; Acoustics; Antiviral activity; Antiviral drugs; Coronaviruses; COVID-19 - drug therapy; High-throughput screening; High-Throughput Screening Assays - methods; Humans; label-free; main protease; Protease; Protease inhibitors; Protease Inhibitors - chemistry; Protease Inhibitors - pharmacology; Proteinase inhibitors; SARS-CoV-2; Screening; Severe acute respiratory syndrome coronavirus 2; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CL protease; Substrates; acoustic ejection MS; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CL protease; label-free; main protease; high-throughput screening