Melanogenesis Promoting Effect, Antioxidant Activity, and UPLC-ESI-HRMS Characterization of Phenolic Compounds of Argan Leaves Extract

• Published in: Molecules (Basel, Switzerland) Vol. 26; no. 2; p. 371
• Main Authors: Bourhim, Thouria, Villareal, Myra O, Couderc, François, Hafidi, Abdellatif, Isoda, Hiroko, Gadhi, Chemseddoha
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 12.01.2021; MDPI AG
• Subjects: Animals; antioxidant activity; Antioxidants - pharmacology; argan leaves; Cell Death - drug effects; Cell Survival - drug effects; Chemical Sciences; Chromatography, High Pressure Liquid; Dermatology; Human health and pathology; Intramolecular Oxidoreductases - metabolism; Life Sciences; Medicinal Chemistry; Melanins - biosynthesis; melanogenesis stimulation; Melanoma, Experimental - pathology; Mice; Monophenol Monooxygenase - metabolism; Oxidoreductases - metabolism; phenolic compounds; Phenols - analysis; Plant Leaves - chemistry; Sapotaceae - chemistry; Spectrometry, Mass, Electrospray Ionization; UPLC-ESI-HRMS; phenolic compounds; melanogenesis stimulation; argan leaves; UPLC-ESI-HRMS; antioxidant activity

The use of natural products for the regulation of skin pigmentation is gaining popularity. In the present study, we evaluated the effect of argan leaves extract (ALE) on melanogenesis in B16 melanoma cells, determined its antioxidant activity, then quantified and identified its phenolic components....