First-in-human autologous implantation of genetically modified adipocytes expressing LCAT for the treatment of familial LCAT deficiency - Aso, Masayuki; Yamamoto, Tokuo T.; Kuroda, Masayuki; Wada, Jun; Kubota, Yoshitaka; Ishikawa, Ko; Maezawa, Yoshiro; Teramoto, Naoya; Tawada, Ayako; Asada, Sakiyo; Aoyagi, Yasuyuki; Kirinashizawa, Mika; et al. (Heliyon, 2022)
Keywords: adipocytes; antihypertensive agents; blood pressure; blood serum; cholesterol; cholesterol acyltransferase; Cholesterol homeostasis; cornea; Ex vivo gene therapy; Familial LCAT deficiency; gene therapy; genes; genetic disorders; haptoglobins; HDL; hemoglobin; hemolytic anemia; hypertension; LCAT; lecithins; lipoproteins; opacity; patients; Proteinuria; Renal injury; Renal injury; HDL; Familial LCAT deficiency; LCAT; Ex vivo gene therapy; Cholesterol homeostasis; Proteinuria