Neural responses in autism during movie watching: Inter-individual response variability co-varies with symptomatology

• Published in: NeuroImage (Orlando, Fla.) Vol. 216; p. 116571
• Main Authors: Bolton, Thomas A.W., Freitas, Lorena G.A., Jochaut, Delphine, Giraud, Anne-Lise, Van De Ville, Dimitri
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2020; Elsevier Limited; Elsevier
• Subjects: Adolescent; Adult; Auditory Perception - physiology; Autism; Autism spectrum disorder; Autism Spectrum Disorder - physiopathology; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - physiopathology; Cognitive science; Cognitive Sciences; Connectome - methods; Documentary films; Dynamic functional connectivity; Humans; Inter-subject functional correlation; Life Sciences; Magnetic Resonance Imaging - methods; Male; Motion Pictures; Movie watching; Naturalistic imaging; Neurons and Cognition; Neuroscience; Paradigms; Partial least squares; Social Perception; State analysis; Studies; Symptomatology; Verbal communication; Visual Perception - physiology; Young Adult; Young adults; Symptomatology; Naturalistic imaging; Inter-subject functional correlation; State analysis; Movie watching; Dynamic functional connectivity; Partial least squares; Autism spectrum disorder; Movie watching Symptomatology

Naturalistic movie paradigms are exquisitely dynamic by nature, yet dedicated analytical methods typically remain static. Here, we deployed a dynamic inter-subject functional correlation (ISFC) analysis to study movie-driven functional brain changes in a population of male young adults diagnosed wit...