White Coat Adherence over the First Year of Therapy in Pediatric Epilepsy

To examine white coat adherence over time in children with epilepsy. This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (Mage = 7.2 ± 2.9 years; 38% female) an...

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Published in	The Journal of pediatrics Vol. 161; no. 4; pp. 695 - 699.e1
Main Authors	Modi, Avani C., Ingerski, Lisa M., Rausch, Joseph R., Glauser, Tracy A., Drotar, Dennis
Format	Journal Article
Language	English
Published	Maryland Heights, MO Elsevier Inc 01.10.2012 Mosby, Inc Elsevier
Subjects	Anticonvulsants Anticonvulsants - therapeutic use Biological and medical sciences caregivers Child Child, Preschool children Communication decision making drug therapy epilepsy Epilepsy - drug therapy Female General aspects Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Health participants Humans Logistic Models Male Medical sciences monitoring Nervous system (semeiology, syndromes) Neurology Office Visits Patient Compliance Patient Compliance - statistics & numerical data Pediatrics prospective studies Public health. Hygiene Public health. Hygiene-occupational medicine regression analysis statistics & numerical data therapeutic use MEMS Medication event monitoring systems Human Pediatrics Nervous system diseases Treatment Health staff Epilepsy Central nervous system disease Treatment compliance Adhesion Child Cerebral disorder
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Abstract	To examine white coat adherence over time in children with epilepsy. This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (Mage = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed. Results demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit. White coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits.
AbstractList	OBJECTIVE: To examine white coat adherence over time in children with epilepsy. STUDY DESIGN: This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (Mₐgₑ = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed. RESULTS: Results demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit. CONCLUSIONS: White coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits. Objective To examine white coat adherence over time in children with epilepsy. Study design This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (Mage = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed. Results Results demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit. Conclusions White coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits. To examine white coat adherence over time in children with epilepsy.OBJECTIVETo examine white coat adherence over time in children with epilepsy.This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (M(age) = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed.STUDY DESIGNThis was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (M(age) = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed.Results demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit.RESULTSResults demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit.White coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits.CONCLUSIONSWhite coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits. To examine white coat adherence over time in children with epilepsy. This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (Mage = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed. Results demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit. White coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits. To examine white coat adherence over time in children with epilepsy. This was a longitudinal prospective study to examine medication adherence prior to and following consecutive clinic visits over a 13-month period in 120 children with newly diagnosed epilepsy (M(age) = 7.2 ± 2.9 years; 38% female) and their caregivers. Electronic monitors were used to assess adherence and ordinal logistic regression models were employed. Results demonstrated white coat adherence, with adherence increasing during the 3 days preceding clinic visits. Data also revealed a significant interaction, whereby adherence increased following initial clinic visits, but decreased following the last clinic visit. White coat adherence occurs for children with newly diagnosed epilepsy. Increased awareness of white coat adherence has important implications for clinical decision-making and should be examined in other pediatric populations. Increased monitoring of medication patterns can help clinicians avoid unnecessary changes to the treatment regimen. Interventions targeting improved communication around adherence behaviors are necessary to maximize therapy benefits.
Author	Glauser, Tracy A. Ingerski, Lisa M. Rausch, Joseph R. Modi, Avani C. Drotar, Dennis
Author_xml	– sequence: 1 givenname: Avani C. surname: Modi fullname: Modi, Avani C. email: avani.modi@cchmc.org organization: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH – sequence: 2 givenname: Lisa M. surname: Ingerski fullname: Ingerski, Lisa M. organization: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH – sequence: 3 givenname: Joseph R. surname: Rausch fullname: Rausch, Joseph R. organization: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH – sequence: 4 givenname: Tracy A. surname: Glauser fullname: Glauser, Tracy A. organization: Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH – sequence: 5 givenname: Dennis surname: Drotar fullname: Drotar, Dennis organization: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
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Snippet	To examine white coat adherence over time in children with epilepsy. This was a longitudinal prospective study to examine medication adherence prior to and... Objective To examine white coat adherence over time in children with epilepsy. Study design This was a longitudinal prospective study to examine medication... OBJECTIVE: To examine white coat adherence over time in children with epilepsy. STUDY DESIGN: This was a longitudinal prospective study to examine medication... To examine white coat adherence over time in children with epilepsy.OBJECTIVETo examine white coat adherence over time in children with epilepsy.This was a...
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SubjectTerms	Anticonvulsants Anticonvulsants - therapeutic use Biological and medical sciences caregivers Child Child, Preschool children Communication decision making drug therapy epilepsy Epilepsy - drug therapy Female General aspects Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Health participants Humans Logistic Models Male Medical sciences monitoring Nervous system (semeiology, syndromes) Neurology Office Visits Patient Compliance Patient Compliance - statistics & numerical data Pediatrics prospective studies Public health. Hygiene Public health. Hygiene-occupational medicine regression analysis statistics & numerical data therapeutic use
Title	White Coat Adherence over the First Year of Therapy in Pediatric Epilepsy
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