Intestinal microbiota has important effect on severity of hand foot and mouth disease in children

• Published in: BMC infectious diseases Vol. 21; no. 1; pp. 1 - 16
• Main Authors: Shen, Chenguang, Xu, Yi, Ji, Jingkai, Wei, Jinli, Jiang, Yujin, Yang, Yang, Yang, Minghui, Huang, Huaxin, Zou, Rongrong, Fang, Chunxiao, Zeng, Fansen, Yang, Fengxia, Wang, Xinfa, Yuan, Jing, Li, Jianmin, Wang, Xianfeng, Yang, Huanming, Gong, Sitang, Wang, Hui, Xia, Huimin, Ma, Jinmin, Liu, Yingxia
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 13.10.2021; BioMed Central; BMC
• Subjects: Bacteroides; Bacteroides and Clostridium; Care and treatment; Children; Clostridium; Clustering; Coxsackievirus infections; Development and progression; Diagnosis; Diseases; Enrichment; Enteroviruses; Feces; Gastrointestinal system; Gastrointestinal tract; Gene expression; Genes; Genomes; Genomics; Genotypes; Hand foot and mouth disease; Health aspects; Hospitals; Infectious diseases; Intestinal microflora; Intestinal microorganisms; Intestine; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Pathogens; Predictive markers; Prognosis; Signs and symptoms; Viruses; China; United States > US

The incidence of hand foot and mouth disease (HFMD) has increased in recent years, making it a very common childhood illness worldwide. The relationship between different enterovirus genotypes and disease severity is not clearly understood. Given that enteroviruses are transmitted through the gastro...