The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

• Published in: The ISME Journal Vol. 6; no. 7; pp. 1415 - 1426
• Main Authors: Zoetendal, Erwin G, Raes, Jeroen, van den Bogert, Bartholomeus, Arumugam, Manimozhiyan, Booijink, Carien CGM, Troost, Freddy J, Bork, Peer, Wels, Michiel, de Vos, Willem M, Kleerebezem, Michiel
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2012; Oxford University Press; Nature Publishing Group
• Subjects: 631/158/855; 631/208/212/2306; 631/326/41/2142; 692/698/2741/2135; Adult; bacterial diversity; Biomedical and Life Sciences; Biotin; Carbohydrate Metabolism; Carbohydrates; Clostridium; Clostridium - genetics; Clostridium - isolation & purification; Clostridium - metabolism; Colon; Colon - microbiology; E coli; Ecological models; Ecology; Ecosystem; Effluents; Escherichia coli; Escherichia coli - genetics; Escherichia coli - isolation & purification; Escherichia coli - metabolism; Evolutionary Biology; Fatty acids; Female; Fermentation; fragment-length-polymorphism; Gastrointestinal tract; gut microbiome; human gastrointestinal-tract; human ileal; Humans; Ileostomy; Intestinal microflora; Intestine, Small - microbiology; Life Sciences; Male; Metabolism; Metagenome; microarray analysis; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Mucosa; Original; original-article; phosphotransferase; Phylogeny; samples; sequence data; Small intestine; Streptococcus; Streptococcus - genetics; Streptococcus - isolation & purification; Streptococcus - metabolism; twins; microbiota; phylogeny; small intestine; ecological model; function

The human gastrointestinal tract (GI tract) harbors a complex community of microbes. The microbiota composition varies between different locations in the GI tract, but most studies focus on the fecal microbiota, and that inhabiting the colonic mucosa. Consequently, little is known about the microbio...