Transplantation of autologous chondrocytes ex-vivo expanded using Thermoreversible Gelation Polymer in a rabbit model of articular cartilage defect

• Published in: Journal of Orthopaedics Vol. 14; no. 2; pp. 223 - 225
• Main Authors: Arumugam, Sivaraman, Bhupesh Karthik, Balasubramanyan, Chinnuswami, Rajeswar, Mori, Yuichi, Yoshioka, Hiroshi, Senthilkumar, Rajappa, Mathaiyan, Rajmohan, Ramalingam, Karthick, Senthilkumar, Preethy, Abraham, Samuel J.K.
• Format: Journal Article
• Language: English
• Published: India Elsevier India Pvt Ltd 01.06.2017; Elsevier BV; Elsevier
• Subjects: Articular cartilage; Autologous chondrocyte implantation (ACI); De-differentiation; Orthopedics; Short Report; Thermo-reversible gelation polymer (TGP); Tissue engineering; Articular cartilage; Autologous chondrocyte implantation (ACI); Thermo-reversible gelation polymer (TGP); Tissue engineering; De-differentiation

Graft failure due to de-differentiation of the chondrocytes during in vitro culture and after transplantation is a major hurdle in Autologous Chondrocyte Implantation (ACI). We, herein, report the transplantation of autologous chondrocytes ex vivo expanded using a Thermo-reversible Gelation Polymer...