Probiotic supplementation attenuates age‐related sarcopenia via the gut–muscle axis in SAMP8 mice

• Published in: Journal of cachexia, sarcopenia and muscle Vol. 13; no. 1; pp. 515 - 531
• Main Authors: Chen, Li‐Han, Chang, Shy‐Shin, Chang, Hsin‐Yi, Wu, Chieh‐Hsi, Pan, Chun‐Hsu, Chang, Chun‐Chao, Chan, Ching‐Hung, Huang, Hui‐Yu
• Format: Journal Article
• Language: English
• Published: Germany John Wiley & Sons, Inc 01.02.2022; John Wiley and Sons Inc; Wiley
• Subjects: Age; Age‐related sarcopenia; Animals; Body composition; Cytokines; Fatty acids; Gene expression; Gut microbiota; Gut–muscle axis; Hypotheses; Inflammation; Mice; Microbiota; Mitochondria; Mitochondrial DNA; Muscle function; Muscle strength; Muscles; Musculoskeletal system; Older people; Original; Original : Basic Science; Oxidative stress; Probiotics; Probiotics - therapeutic use; Proteins; Quality of Life; Reactive oxygen species; RNA, Ribosomal, 16S - genetics; Sarcopenia; Sarcopenia - therapy; Senescence; Short‐chain fatty acid; United States > US; Taiwan; Gut microbiota; Probiotics; Short-chain fatty acid; Age-related sarcopenia; Gut-muscle axis

Background Age‐related muscle dysfunctions are common disorders resulting in poor quality of life in the elderly. Probiotic supplementation is a potential strategy for preventing age‐related sarcopenia as evidence suggests that probiotics can enhance muscle function via the gut–muscle axis. However,...