Peak width of skeletonized mean diffusivity and its association with age-related cognitive alterations and vascular risk factors

• Published in: Alzheimer's & dementia : diagnosis, assessment & disease monitoring Vol. 11; no. 1; pp. 721 - 729
• Main Authors: Lam, Bonnie Yin Ka, Leung, Kam Tat, Yiu, Brian, Zhao, Lei, Biesbroek, J. Matthijs, Au, Lisa, Tang, Yumi, Wang, Kai, Fan, Yuhua, Fu, Jian-Hui, Xu, Qun, Song, Haiqing, Tian, Xiaolin, Chu, Winnie Chiu Wing, Abrigo, Jill, Shi, Lin, Ko, Ho, Lau, Alexander, Duering, Marco, Wong, Adrian, Mok, Vincent Chung Tong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2019; Elsevier; Wiley
• Subjects: Community subjects; Diffusion tensor imaging; Neuroimaging; Peak width of skeletonized mean diffusivity; Processing speed; Small vessel disease; Peak width of skeletonized mean diffusivity; Processing speed; Small vessel disease; Community subjects; Diffusion tensor imaging

Only two studies investigated the associations between peak width of skeletonized mean diffusivity (PSMD) and age-related cognitive alterations, whereas none of the studies investigated the association with vascular risk factors. We evaluated 801 stroke- and dementia-free elderlies with baseline and...