Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules - Cicone, Francesco; Viertl, David; Denoël, Thibaut; Stabin, Michael G.; Prior, John O.; Gnesin, Silvano (EJNMMI research, 2022)
Keywords: Activity coefficients; Algorithms; Allometric equations; Biodistribution; Cardiac Imaging; Comparative studies; Dose extrapolations; Dosimeters; Dosimetry; Extrapolation; Imaging; Laboratory animals; Macromolecules; Medicine; Medicine & Public Health; Metabolism; Mouse devices; Nuclear Medicine; Oncology; Organs; Original Research; Orthopedics; Parameters; Preclinical models; Radiology; Radiopharmaceuticals; Scaling; Scaling factor; Small animal dosimetry; Toxicity; Metabolic time scaling; Dose extrapolations; Small animal dosimetry; Scaling factor; Allometric equations; OLINDA/EXM® 2.0; Mass scaling; Radiopharmaceuticals; Preclinical models; Biodistribution