TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis - Cignarella, Francesca; Filipello, Fabia; Bollman, Bryan; Cantoni, Claudia; Locca, Alberto; Mikesell, Robert; Manis, Melissa; Ibrahim, Adiljan; Deng, Li; Benitez, Bruno A.; Cruchaga, Carlos; Licastro, Danilo; et al. (Acta neuropathologica, 2020)
Keywords: Adult; Aged; Analysis; Animals; Antibodies; Central nervous system; Cuprizone; Demyelination; Disease Models, Animal; Ethylenediaminetetraacetic acid; Female; Gene expression; Glial stem cells; Humans; Macrophages; Male; Medicine; Medicine & Public Health; Membrane Glycoproteins - metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Microglia - metabolism; Middle Aged; Multiple sclerosis; Multiple Sclerosis - metabolism; Multiple Sclerosis - pathology; Myelin; Myelin Sheath - metabolism; Myelin Sheath - pathology; Myelination; Neurodegenerative diseases; Neurosciences; Oligodendrocytes; Original Paper; Pathology; Phagocytes; Phagocytosis - physiology; Receptors, Immunologic - metabolism; Remyelination - physiology; Viral antibodies