Divergent sequences of tetraspanins enable plants to specifically recognize microbe-derived extracellular vesicles

Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean ( Glycine max ) root rot pathogen Phytophthora sojae ident...

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Published inNature communications Vol. 14; no. 1; pp. 4877 - 14
Main Authors Zhu, Jinyi, Qiao, Qian, Sun, Yujing, Xu, Yuanpeng, Shu, Haidong, Zhang, Zhichao, Liu, Fan, Wang, Haonan, Ye, Wenwu, Dong, Suomeng, Wang, Yan, Ma, Zhenchuan, Wang, Yuanchao
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 12.08.2023
Nature Publishing Group
Nature Portfolio
Subjects
14/19
14/28
14/35
38/22
38/77
38/88
38/90
631/449/2169/2673
631/449/2169/2674
631/449/2661/2666
82/58
82/80
82/83
Amino acids
Cell interactions
Divergence
Eukaryotes
Extracellular
Extracellular vesicles
Extracellular Vesicles - metabolism
Glycine max - metabolism
Humanities and Social Sciences
Immune response
Immune system
Innate immunity
Kinases
Microorganisms
multidisciplinary
Nicotiana benthamiana
Pathogens
Phytophthora - physiology
Phytophthora sojae
Plant cells
Plant Diseases - microbiology
Plant immunity
Plant Proteins - genetics
Plant Proteins - metabolism
Plants
Proteins
Proteomics
Root rot
Science
Science (multidisciplinary)
Sequences
Soybeans
Vesicles
Virulence
Online AccessGet full text

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Abstract Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean ( Glycine max ) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae . The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes. Extracellular vesicles (EVs) are important in plant-microbe interactions. Here we show that the divergent sequences within tetraspanins localized at EV membranes enable plant innate immune system to distinguish between self and non-self EVs.
AbstractList Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean (Glycine max) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae. The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.Extracellular vesicles (EVs) are important in plant-microbe interactions. Here we show that the divergent sequences within tetraspanins localized at EV membranes enable plant innate immune system to distinguish between self and non-self EVs.
Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant-microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean (Glycine max) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae. The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant-microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean (Glycine max) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae. The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.
Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean ( Glycine max ) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae . The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.
Abstract Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean (Glycine max) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae. The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.
Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean ( Glycine max ) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae . The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes. Extracellular vesicles (EVs) are important in plant-microbe interactions. Here we show that the divergent sequences within tetraspanins localized at EV membranes enable plant innate immune system to distinguish between self and non-self EVs.
Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant-microbe interactions, but the underlying mechanisms remain elusive. Here, proteomic analyses of EVs from the soybean (Glycine max) root rot pathogen Phytophthora sojae identify the tetraspanin family proteins PsTET1 and PsTET3, which are recognized by Nicotiana benthamiana to trigger plant immune responses. Both proteins are required for the full virulence of P. sojae. The large extracellular loop (EC2) of PsTET3 is the key region recognized by N. benthamiana and soybean cells in a plant receptor-like kinase NbSERK3a/b dependent manner. TET proteins from oomycete and fungal plant pathogens are recognized by N. benthamiana thus inducing immune responses, whereas plant-derived TET proteins are not due to the sequence divergence of sixteen amino acids at the C-terminal of EC2. This feature allows plants to distinguish self and non-self EVs to trigger active defense responses against pathogenic eukaryotes.
ArticleNumber 4877
Author Xu, Yuanpeng
Qiao, Qian
Liu, Fan
Sun, Yujing
Dong, Suomeng
Wang, Yan
Zhang, Zhichao
Ma, Zhenchuan
Ye, Wenwu
Shu, Haidong
Wang, Yuanchao
Zhu, Jinyi
Wang, Haonan
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/37573360$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1016/j.tcb.2009.06.004
10.3389/fpls.2019.01610
10.1111/nph.16650
10.1093/plphys/kiab239
10.1128/EC.00370-07
10.3389/fmicb.2021.645331
10.1016/j.cell.2019.02.029
10.1104/pp.18.01557
10.1038/nmeth.1322
10.1038/s41467-020-15459-7
10.1002/cpmc.25
10.1016/j.biotechadv.2022.107934
10.1111/febs.12110
10.1371/journal.ppat.1004491
10.3389/fmicb.2022.817844
10.1038/nbt.1511
10.1073/pnas.111132998
10.1371/journal.ppat.1005793
10.1038/nprot.2014.092
10.1105/tpc.104.026765
10.1073/pnas.1521230113
10.1094/MPMI-12-15-0270-R
10.1016/j.celrep.2020.108645
10.1083/jcb.201211138
10.1046/j.1365-313X.1999.00265.x
10.1093/jxb/erx355
10.1111/nph.14696
10.1126/science.aar4142
10.1016/j.jprot.2021.104137
10.3389/fmicb.2020.00432
10.1111/nph.15631
10.1093/nar/gkab1038
10.1111/tra.12245
10.1186/1471-2164-9-63
10.1111/j.1574-6968.2006.00128.x
10.1111/mpp.13028
10.1016/j.cell.2016.09.056
10.1111/mpp.12318
10.1371/journal.pone.0016608
10.1016/j.molp.2020.07.016
10.1016/j.ygeno.2005.08.004
10.1111/jipb.13181
10.1111/mpp.12805
10.1007/s00018-011-0689-3
10.1104/pp.16.01253
10.1093/plcell/koab276
10.1016/j.chom.2018.11.007
10.1038/s41477-021-00863-8
10.1074/jbc.M112.445304
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References Wiśniewski, Zougman, Nagaraj, Mann (CR49) 2009; 6
Bleackley (CR20) 2019; 10
Wang (CR14) 2017; 216
Wang (CR25) 2018; 9
Fang, Wang, Zhang, Peng, Liu (CR13) 2021; 238
Tran (CR23) 2022; 34
Veneault-Fourrey, Lambou, Lebrun (CR31) 2006; 256
Bahar (CR21) 2016; 29
Felix, Duran, Volko, Boller (CR28) 1999; 18
Cox, Mann (CR50) 2008; 26
Perez-Riverol (CR51) 2022; 50
Liu (CR41) 2020; 13
He (CR36) 2021; 7
Cai (CR10) 2018; 360
Bozkurt (CR6) 2015; 16
Fang, Wang, Liu, Tyler (CR1) 2022; 13
Clergeot (CR44) 2001; 98
Qiu, Li, Ye, Zheng, Wang (CR45) 2021; 22
Senthil-Kumar, Mysore (CR47) 2014; 9
Chaparro-Garcia (CR24) 2011; 6
Fang, Cui, Gu, Arredondo, Tyler (CR26) 2017; 44
Kowal (CR16) 2016; 113
Böhm (CR35) 2014; 10
Janda, Robatzek (CR4) 2022; 58
Rutter, Innes (CR7) 2017; 173
Mazurov, Barbashova, Filatov (CR40) 2013; 280
Caruana, Walper (CR37) 2020; 11
Fang, Tyler (CR27) 2016; 17
Gu (CR46) 2021; 12
Umeda (CR29) 2020; 11
Hill, Solomon (CR33) 2020; 7
Kunze (CR34) 2004; 16
Zimmerman (CR30) 2016; 167
Lambou (CR19) 2008; 9
Nie, Yin, Li, Wu, Huang (CR32) 2019; 222
Jeppesen (CR17) 2019; 177
Rodrigues (CR12) 2008; 7
Raposo, Stoorvogel (CR3) 2013; 200
Rybak, Robatzek (CR5) 2019; 179
Yáñez-Mó, Barreiro, Gordon-Alonso, Sala-Valdés, Sánchez-Madrid (CR18) 2009; 19
McMillan, Zebell, Ristaino, Dong, Kuehn (CR22) 2021; 34
De Palma (CR8) 2020; 9
Green, Eaton, Savoian, Scott (CR42) 2019; 20
Huang (CR38) 2005; 86
Huang, Wang, Cai, Jin (CR48) 2021; 63
György (CR2) 2011; 68
Perez-Hernandez (CR39) 2013; 288
Xu (CR52) 2021; 187
Boevink, Birch, Turnbull, Whisson (CR15) 2020; 228
Zhao, Zhou, Guo (CR43) 2016; 12
Regente (CR9) 2017; 68
Hou (CR11) 2019; 25
M Janda (40623_CR4) 2022; 58
H Böhm (40623_CR35) 2014; 10
BD Rutter (40623_CR7) 2017; 173
JR Wiśniewski (40623_CR49) 2009; 6
Y Hou (40623_CR11) 2019; 25
YL Zhao (40623_CR43) 2016; 12
M Senthil-Kumar (40623_CR47) 2014; 9
C Veneault-Fourrey (40623_CR31) 2006; 256
ML Rodrigues (40623_CR12) 2008; 7
Y Huang (40623_CR48) 2021; 63
B György (40623_CR2) 2011; 68
J Cox (40623_CR50) 2008; 26
M Yáñez-Mó (40623_CR18) 2009; 19
PC Boevink (40623_CR15) 2020; 228
TO Bozkurt (40623_CR6) 2015; 16
PH Clergeot (40623_CR44) 2001; 98
K Rybak (40623_CR5) 2019; 179
Y Fang (40623_CR1) 2022; 13
B He (40623_CR36) 2021; 7
Y Fang (40623_CR13) 2021; 238
B Zimmerman (40623_CR30) 2016; 167
M Qiu (40623_CR45) 2021; 22
Y Perez-Riverol (40623_CR51) 2022; 50
Q Cai (40623_CR10) 2018; 360
D Mazurov (40623_CR40) 2013; 280
MR Bleackley (40623_CR20) 2019; 10
Y Xu (40623_CR52) 2021; 187
R Umeda (40623_CR29) 2020; 11
HM McMillan (40623_CR22) 2021; 34
Y Fang (40623_CR26) 2017; 44
M Regente (40623_CR9) 2017; 68
G Felix (40623_CR28) 1999; 18
S Wang (40623_CR14) 2017; 216
J Kowal (40623_CR16) 2016; 113
JC Caruana (40623_CR37) 2020; 11
K Lambou (40623_CR19) 2008; 9
B Gu (40623_CR46) 2021; 12
Y Wang (40623_CR25) 2018; 9
G Raposo (40623_CR3) 2013; 200
D Perez-Hernandez (40623_CR39) 2013; 288
O Bahar (40623_CR21) 2016; 29
KA Green (40623_CR42) 2019; 20
M De Palma (40623_CR8) 2020; 9
Y Fang (40623_CR27) 2016; 17
J Nie (40623_CR32) 2019; 222
G Kunze (40623_CR34) 2004; 16
EH Hill (40623_CR33) 2020; 7
TM Tran (40623_CR23) 2022; 34
NJ Liu (40623_CR41) 2020; 13
A Chaparro-Garcia (40623_CR24) 2011; 6
DK Jeppesen (40623_CR17) 2019; 177
S Huang (40623_CR38) 2005; 86
References_xml – volume: 256
  start-page: 179
  year: 2006
  end-page: 184
  ident: CR31
  article-title: Fungal Pls1 tetraspanins as key factors of penetration into host plants: a role in re-establishing polarized growth in the appressorium?
  publication-title: FEMS Microbiol. Lett.
– volume: 187
  start-page: 321
  year: 2021
  end-page: 335
  ident: CR52
  article-title: apoplastic effector AEP1 mediates sugar uptake by mutarotation of extracellular aldose and is recognized as a MAMP
  publication-title: Plant Physiol.
– volume: 9
  start-page: 1777
  year: 2020
  ident: CR8
  article-title: Plant roots release small extracellular vesicles with antifungal activity
  publication-title: Plants (Basel, Switzerland)
– volume: 6
  start-page: e16608
  year: 2011
  ident: CR24
  article-title: The receptor-like kinase SERK3/BAK1 is required for basal resistance against the late blight pathogen phytophthora infestans in
  publication-title: PLoS ONE
– volume: 200
  start-page: 373
  year: 2013
  end-page: 383
  ident: CR3
  article-title: Extracellular vesicles: exosomes, microvesicles, and friends
  publication-title: J. Cell Biol.
– volume: 68
  start-page: 2667
  year: 2011
  end-page: 2688
  ident: CR2
  article-title: Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
  publication-title: Cell. Mol. life Sci.
– volume: 44
  start-page: 21a.21.21
  year: 2017
  end-page: 21a.21.26
  ident: CR26
  article-title: Efficient genome editing in the Oomycete using CRISPR/Cas9
  publication-title: Curr. Protoc. Microbiol.
– volume: 177
  start-page: 428
  year: 2019
  end-page: 445.e418
  ident: CR17
  article-title: Reassessment of exosome composition
  publication-title: Cell
– volume: 173
  start-page: 728
  year: 2017
  end-page: 741
  ident: CR7
  article-title: Extracellular vesicles isolated from the leaf apoplast carry stress-response proteins
  publication-title: Plant Physiol.
– volume: 34
  start-page: 395
  year: 2022
  end-page: 417
  ident: CR23
  article-title: Potentiation of plant defense by bacterial outer membrane vesicles is mediated by membrane nanodomains
  publication-title: Plant Cell
– volume: 9
  year: 2018
  ident: CR25
  article-title: Leucine-rich repeat receptor-like gene screen reveals that Nicotiana RXEG1 regulates glycoside hydrolase 12 MAMP detection
  publication-title: Nat. Commun.
– volume: 238
  start-page: 104137
  year: 2021
  ident: CR13
  article-title: Characterization and proteome analysis of the extracellular vesicles of
  publication-title: J. Proteom.
– volume: 16
  start-page: 3496
  year: 2004
  end-page: 3507
  ident: CR34
  article-title: The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants
  publication-title: Plant Cell
– volume: 10
  start-page: 1610
  year: 2019
  ident: CR20
  article-title: Extracellular vesicles from the cotton pathogen f. sp. induce a phytotoxic response in plants
  publication-title: Front. Plant Sci.
– volume: 18
  start-page: 265
  year: 1999
  end-page: 276
  ident: CR28
  article-title: Plants have a sensitive perception system for the most conserved domain of bacterial flagellin
  publication-title: Plant J.: Cell Mol. Biol.
– volume: 167
  start-page: 1041
  year: 2016
  end-page: 1051.e1011
  ident: CR30
  article-title: Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket
  publication-title: Cell
– volume: 22
  start-page: 373
  year: 2021
  end-page: 381
  ident: CR45
  article-title: A CRISPR/Cas9-mediated in situ complementation method for mutants
  publication-title: Mol. Plant Pathol.
– volume: 360
  start-page: 1126
  year: 2018
  end-page: 1129
  ident: CR10
  article-title: Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
  publication-title: Science
– volume: 7
  start-page: 342
  year: 2021
  end-page: 352
  ident: CR36
  article-title: RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles
  publication-title: Nat. Plants
– volume: 68
  start-page: 5485
  year: 2017
  end-page: 5495
  ident: CR9
  article-title: Plant extracellular vesicles are incorporated by a fungal pathogen and inhibit its growth
  publication-title: J. Exp. Bot.
– volume: 13
  start-page: 1523
  year: 2020
  end-page: 1532
  ident: CR41
  article-title: Lipidomic analysis reveals the importance of GIPCs in Arabidopsis leaf extracellular vesicles
  publication-title: Mol. Plant
– volume: 7
  start-page: 58
  year: 2008
  end-page: 67
  ident: CR12
  article-title: Extracellular vesicles produced by contain protein components associated with virulence
  publication-title: Eukaryot. Cell
– volume: 222
  start-page: 995
  year: 2019
  end-page: 1011
  ident: CR32
  article-title: A small cysteine-rich protein from two kingdoms of microbes is recognized as a novel pathogen-associated molecular pattern
  publication-title: N. Phytologist
– volume: 10
  start-page: e1004491
  year: 2014
  ident: CR35
  article-title: A conserved peptide pattern from a widespread microbial virulence factor triggers pattern-induced immunity in Arabidopsis
  publication-title: PLoS Pathog.
– volume: 9
  start-page: 1549
  year: 2014
  end-page: 1562
  ident: CR47
  article-title: Tobacco rattle virus-based virus-induced gene silencing in
  publication-title: Nat. Protoc.
– volume: 19
  start-page: 434
  year: 2009
  end-page: 446
  ident: CR18
  article-title: Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes
  publication-title: Trends Cell Biol.
– volume: 12
  start-page: 645331
  year: 2021
  ident: CR46
  article-title: Transcriptional variability associated with CRISPR-mediated gene replacements at the Avr1b-1 locus
  publication-title: Front. Microbiol.
– volume: 13
  start-page: 817844
  year: 2022
  ident: CR1
  article-title: Biogenesis and biological functions of extracellular vesicles in cellular and organismal communication with microbes
  publication-title: Front. Microbiol.
– volume: 86
  start-page: 674
  year: 2005
  end-page: 684
  ident: CR38
  article-title: The phylogenetic analysis of tetraspanins projects the evolution of cell-cell interactions from unicellular to multicellular organisms
  publication-title: Genomics
– volume: 113
  start-page: E968
  year: 2016
  end-page: E977
  ident: CR16
  article-title: Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
  publication-title: Proc. Natl Acad. Sci. USA
– volume: 9
  year: 2008
  ident: CR19
  article-title: Fungi have three tetraspanin families with distinct functions
  publication-title: BMC Genomics
– volume: 11
  start-page: 432
  year: 2020
  ident: CR37
  article-title: Bacterial membrane vesicles as mediators of microbe - microbe and microbe–host community interactions
  publication-title: Front. Microbiol.
– volume: 17
  start-page: 127
  year: 2016
  end-page: 139
  ident: CR27
  article-title: Efficient disruption and replacement of an effector gene in the oomycete using CRISPR/Cas9
  publication-title: Mol. plant Pathol.
– volume: 50
  start-page: D543
  year: 2022
  end-page: d552
  ident: CR51
  article-title: The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
  publication-title: Nucleic Acids Res.
– volume: 7
  year: 2020
  ident: CR33
  article-title: Extracellular vesicles from the apoplastic fungal wheat pathogen
  publication-title: Fungal Biol. Biotechnol.
– volume: 11
  year: 2020
  ident: CR29
  article-title: Structural insights into tetraspanin CD9 function
  publication-title: Nat. Commun.
– volume: 216
  start-page: 205
  year: 2017
  end-page: 215
  ident: CR14
  article-title: Delivery of cytoplasmic and apoplastic effectors from haustoria by distinct secretion pathways
  publication-title: N. Phytologist
– volume: 280
  start-page: 1200
  year: 2013
  end-page: 1213
  ident: CR40
  article-title: Tetraspanin protein CD9 interacts with metalloprotease CD10 and enhances its release via exosomes
  publication-title: FEBS J.
– volume: 63
  start-page: 2020
  year: 2021
  end-page: 2030
  ident: CR48
  article-title: Effective methods for isolation and purification of extracellular vesicles from plants
  publication-title: J. Integr. Plant Biol.
– volume: 34
  start-page: 108645
  year: 2021
  ident: CR22
  article-title: Protective plant immune responses are elicited by bacterial outer membrane vesicles
  publication-title: Cell Rep.
– volume: 25
  start-page: 153
  year: 2019
  end-page: 165.e155
  ident: CR11
  article-title: A Phytophthora effector suppresses trans-kingdom RNAi to promote disease susceptibility
  publication-title: Cell Host Microbe
– volume: 98
  start-page: 6963
  year: 2001
  end-page: 6968
  ident: CR44
  article-title: PLS1, a gene encoding a tetraspanin-like protein, is required for penetration of rice leaf by the fungal pathogen
  publication-title: Proc. Natl Acad. Sci. USA
– volume: 288
  start-page: 11649
  year: 2013
  end-page: 11661
  ident: CR39
  article-title: The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes
  publication-title: J. Biol. Chem.
– volume: 228
  start-page: 445
  year: 2020
  end-page: 458
  ident: CR15
  article-title: Devastating intimacy: the cell biology of plant-Phytophthora interactions
  publication-title: N. Phytologist
– volume: 6
  start-page: 359
  year: 2009
  end-page: 362
  ident: CR49
  article-title: Universal sample preparation method for proteome analysis
  publication-title: Nat. Methods
– volume: 16
  start-page: 204
  year: 2015
  end-page: 226
  ident: CR6
  article-title: Rerouting of plant late endocytic trafficking toward a pathogen interface
  publication-title: Traffic
– volume: 12
  start-page: e1005793
  year: 2016
  ident: CR43
  article-title: Hyphopodium-specific VdNoxB/VdPls1-dependent ROS-Ca signaling is required for plant infection by
  publication-title: PLoS Pathog.
– volume: 26
  start-page: 1367
  year: 2008
  end-page: 1372
  ident: CR50
  article-title: MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
  publication-title: Nat. Biotechnol.
– volume: 58
  start-page: 107934
  year: 2022
  ident: CR4
  article-title: Extracellular vesicles from phytobacteria: properties, functions and uses
  publication-title: Biotechnol. Adv.
– volume: 20
  start-page: 961
  year: 2019
  end-page: 975
  ident: CR42
  article-title: A homologue of the fungal tetraspanin Pls1 is required for Epichloë festucae expressorium formation and establishment of a mutualistic interaction with Lolium perenne
  publication-title: Mol. Plant Pathol.
– volume: 179
  start-page: 1236
  year: 2019
  end-page: 1247
  ident: CR5
  article-title: Functions of extracellular vesicles in immunity and virulence
  publication-title: Plant Physiol.
– volume: 29
  start-page: 374
  year: 2016
  end-page: 384
  ident: CR21
  article-title: Bacterial outer membrane vesicles induce plant immune responses
  publication-title: Mol. Plant-microbe Interactions
– volume: 19
  start-page: 434
  year: 2009
  ident: 40623_CR18
  publication-title: Trends Cell Biol.
  doi: 10.1016/j.tcb.2009.06.004
– volume: 10
  start-page: 1610
  year: 2019
  ident: 40623_CR20
  publication-title: Front. Plant Sci.
  doi: 10.3389/fpls.2019.01610
– volume: 228
  start-page: 445
  year: 2020
  ident: 40623_CR15
  publication-title: N. Phytologist
  doi: 10.1111/nph.16650
– volume: 187
  start-page: 321
  year: 2021
  ident: 40623_CR52
  publication-title: Plant Physiol.
  doi: 10.1093/plphys/kiab239
– volume: 7
  start-page: 58
  year: 2008
  ident: 40623_CR12
  publication-title: Eukaryot. Cell
  doi: 10.1128/EC.00370-07
– volume: 12
  start-page: 645331
  year: 2021
  ident: 40623_CR46
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2021.645331
– volume: 177
  start-page: 428
  year: 2019
  ident: 40623_CR17
  publication-title: Cell
  doi: 10.1016/j.cell.2019.02.029
– volume: 9
  start-page: 1777
  year: 2020
  ident: 40623_CR8
  publication-title: Plants (Basel, Switzerland)
– volume: 179
  start-page: 1236
  year: 2019
  ident: 40623_CR5
  publication-title: Plant Physiol.
  doi: 10.1104/pp.18.01557
– volume: 6
  start-page: 359
  year: 2009
  ident: 40623_CR49
  publication-title: Nat. Methods
  doi: 10.1038/nmeth.1322
– volume: 11
  year: 2020
  ident: 40623_CR29
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-020-15459-7
– volume: 44
  start-page: 21a.21.21
  year: 2017
  ident: 40623_CR26
  publication-title: Curr. Protoc. Microbiol.
  doi: 10.1002/cpmc.25
– volume: 58
  start-page: 107934
  year: 2022
  ident: 40623_CR4
  publication-title: Biotechnol. Adv.
  doi: 10.1016/j.biotechadv.2022.107934
– volume: 7
  year: 2020
  ident: 40623_CR33
  publication-title: Fungal Biol. Biotechnol.
– volume: 280
  start-page: 1200
  year: 2013
  ident: 40623_CR40
  publication-title: FEBS J.
  doi: 10.1111/febs.12110
– volume: 10
  start-page: e1004491
  year: 2014
  ident: 40623_CR35
  publication-title: PLoS Pathog.
  doi: 10.1371/journal.ppat.1004491
– volume: 13
  start-page: 817844
  year: 2022
  ident: 40623_CR1
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2022.817844
– volume: 26
  start-page: 1367
  year: 2008
  ident: 40623_CR50
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.1511
– volume: 98
  start-page: 6963
  year: 2001
  ident: 40623_CR44
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.111132998
– volume: 12
  start-page: e1005793
  year: 2016
  ident: 40623_CR43
  publication-title: PLoS Pathog.
  doi: 10.1371/journal.ppat.1005793
– volume: 9
  start-page: 1549
  year: 2014
  ident: 40623_CR47
  publication-title: Nat. Protoc.
  doi: 10.1038/nprot.2014.092
– volume: 16
  start-page: 3496
  year: 2004
  ident: 40623_CR34
  publication-title: Plant Cell
  doi: 10.1105/tpc.104.026765
– volume: 113
  start-page: E968
  year: 2016
  ident: 40623_CR16
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.1521230113
– volume: 29
  start-page: 374
  year: 2016
  ident: 40623_CR21
  publication-title: Mol. Plant-microbe Interactions
  doi: 10.1094/MPMI-12-15-0270-R
– volume: 34
  start-page: 108645
  year: 2021
  ident: 40623_CR22
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2020.108645
– volume: 200
  start-page: 373
  year: 2013
  ident: 40623_CR3
  publication-title: J. Cell Biol.
  doi: 10.1083/jcb.201211138
– volume: 18
  start-page: 265
  year: 1999
  ident: 40623_CR28
  publication-title: Plant J.: Cell Mol. Biol.
  doi: 10.1046/j.1365-313X.1999.00265.x
– volume: 68
  start-page: 5485
  year: 2017
  ident: 40623_CR9
  publication-title: J. Exp. Bot.
  doi: 10.1093/jxb/erx355
– volume: 216
  start-page: 205
  year: 2017
  ident: 40623_CR14
  publication-title: N. Phytologist
  doi: 10.1111/nph.14696
– volume: 360
  start-page: 1126
  year: 2018
  ident: 40623_CR10
  publication-title: Science
  doi: 10.1126/science.aar4142
– volume: 238
  start-page: 104137
  year: 2021
  ident: 40623_CR13
  publication-title: J. Proteom.
  doi: 10.1016/j.jprot.2021.104137
– volume: 9
  year: 2018
  ident: 40623_CR25
  publication-title: Nat. Commun.
– volume: 11
  start-page: 432
  year: 2020
  ident: 40623_CR37
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2020.00432
– volume: 222
  start-page: 995
  year: 2019
  ident: 40623_CR32
  publication-title: N. Phytologist
  doi: 10.1111/nph.15631
– volume: 50
  start-page: D543
  year: 2022
  ident: 40623_CR51
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkab1038
– volume: 16
  start-page: 204
  year: 2015
  ident: 40623_CR6
  publication-title: Traffic
  doi: 10.1111/tra.12245
– volume: 9
  year: 2008
  ident: 40623_CR19
  publication-title: BMC Genomics
  doi: 10.1186/1471-2164-9-63
– volume: 256
  start-page: 179
  year: 2006
  ident: 40623_CR31
  publication-title: FEMS Microbiol. Lett.
  doi: 10.1111/j.1574-6968.2006.00128.x
– volume: 22
  start-page: 373
  year: 2021
  ident: 40623_CR45
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/mpp.13028
– volume: 167
  start-page: 1041
  year: 2016
  ident: 40623_CR30
  publication-title: Cell
  doi: 10.1016/j.cell.2016.09.056
– volume: 17
  start-page: 127
  year: 2016
  ident: 40623_CR27
  publication-title: Mol. plant Pathol.
  doi: 10.1111/mpp.12318
– volume: 6
  start-page: e16608
  year: 2011
  ident: 40623_CR24
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0016608
– volume: 13
  start-page: 1523
  year: 2020
  ident: 40623_CR41
  publication-title: Mol. Plant
  doi: 10.1016/j.molp.2020.07.016
– volume: 86
  start-page: 674
  year: 2005
  ident: 40623_CR38
  publication-title: Genomics
  doi: 10.1016/j.ygeno.2005.08.004
– volume: 63
  start-page: 2020
  year: 2021
  ident: 40623_CR48
  publication-title: J. Integr. Plant Biol.
  doi: 10.1111/jipb.13181
– volume: 20
  start-page: 961
  year: 2019
  ident: 40623_CR42
  publication-title: Mol. Plant Pathol.
  doi: 10.1111/mpp.12805
– volume: 68
  start-page: 2667
  year: 2011
  ident: 40623_CR2
  publication-title: Cell. Mol. life Sci.
  doi: 10.1007/s00018-011-0689-3
– volume: 173
  start-page: 728
  year: 2017
  ident: 40623_CR7
  publication-title: Plant Physiol.
  doi: 10.1104/pp.16.01253
– volume: 34
  start-page: 395
  year: 2022
  ident: 40623_CR23
  publication-title: Plant Cell
  doi: 10.1093/plcell/koab276
– volume: 25
  start-page: 153
  year: 2019
  ident: 40623_CR11
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2018.11.007
– volume: 7
  start-page: 342
  year: 2021
  ident: 40623_CR36
  publication-title: Nat. Plants
  doi: 10.1038/s41477-021-00863-8
– volume: 288
  start-page: 11649
  year: 2013
  ident: 40623_CR39
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M112.445304
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Snippet Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but the...
Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant-microbe interactions, but the...
Abstract Extracellular vesicles (EVs) are important for cell-to-cell communication in animals. EVs also play important roles in plant–microbe interactions, but...
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Title Divergent sequences of tetraspanins enable plants to specifically recognize microbe-derived extracellular vesicles
URI https://link.springer.com/article/10.1038/s41467-023-40623-0
https://www.ncbi.nlm.nih.gov/pubmed/37573360
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https://pubmed.ncbi.nlm.nih.gov/PMC10423219
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Volume 14
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