Shedding of norovirus in symptomatic and asymptomatic infections

• Published in: Epidemiology and infection Vol. 143; no. 8; pp. 1710 - 1717
• Main Authors: TEUNIS, P. F. M., SUKHRIE, F. H. A., VENNEMA, H., BOGERMAN, J., BEERSMA, M. F. C., KOOPMANS, M. P. G.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.06.2015
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Asymptomatic; Asymptomatic Infections; Bayes Theorem; Caliciviridae Infections - epidemiology; Caliciviridae Infections - transmission; Caliciviridae Infections - virology; Cohort Studies; Consent; Disease Outbreaks; Epidemics; Feces - virology; Female; Gastroenteritis; Gastroenteritis - epidemiology; Gastroenteritis - virology; Gastrointestinal infections; Health Personnel - statistics & numerical data; Hospitals; Humans; Infections; Infectious Disease Transmission, Patient-to-Professional; Infectious Disease Transmission, Professional-to-Patient; Longitudinal Studies; Male; Medical personnel; Middle Aged; Multilevel Analysis; Norovirus; Norovirus - genetics; Nursing Homes; Original Papers; Patients; Real-Time Polymerase Chain Reaction; RNA, Viral - analysis; Transfer RNA; Virus Shedding - physiology; Viruses; Young Adult; gastrointestinal infections; Asymptomatic viral infections; Norwalk agent and related viruses; virology (human) and epidemiology; virus infection

Norovirus is the most frequent cause of acute infectious gastroenteritis and it is difficult to control in crowded environments like hospitals and nursing homes. Transmission depends on oral intake of virus deposited in the environment by infectious subjects. Data from volunteer studies indicate tha...