Rapid evolution of A(H5N1) influenza viruses after intercontinental spread to North America

• Published in: Nature communications Vol. 14; no. 1; pp. 3082 - 13
• Main Authors: Kandeil, Ahmed, Patton, Christopher, Jones, Jeremy C., Jeevan, Trushar, Harrington, Walter N., Trifkovic, Sanja, Seiler, Jon P., Fabrizio, Thomas, Woodard, Karlie, Turner, Jasmine C., Crumpton, Jeri-Carol, Miller, Lance, Rubrum, Adam, DeBeauchamp, Jennifer, Russell, Charles J., Govorkova, Elena A., Vogel, Peter, Kim-Torchetti, Mia, Berhane, Yohannes, Stallknecht, David, Poulson, Rebecca, Kercher, Lisa, Webby, Richard J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 29.05.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 13/106; 13/109; 38/22; 38/23; 631/181/735; 631/326/421; 631/326/596/1578; 64/60; 82/51; 96/63; Animal models; Animals; Animals, Wild; Avian flu; Birds; Central nervous system; Evolution; Explosive cladding; Genotypes; Humanities and Social Sciences; Humans; Influenza; Influenza A; Influenza A virus; Influenza A Virus, H5N1 Subtype - genetics; Influenza in Birds - epidemiology; Influenza, Human - epidemiology; Mammals; multidisciplinary; Pandemics; Phylogeny; Poultry; Science; Science (multidisciplinary); Viruses; North America

Highly pathogenic avian influenza A(H5N1) viruses of clade 2.3.4.4b underwent an explosive geographic expansion in 2021 among wild birds and domestic poultry across Asia, Europe, and Africa. By the end of 2021, 2.3.4.4b viruses were detected in North America, signifying further intercontinental spre...