A New Form of Inherited Red-Blindness Identified in Zebrafish

• Published in: The Journal of neuroscience Vol. 17; no. 11; pp. 4236 - 4242
• Main Authors: Brockerhoff, Susan E, Hurley, James B, Niemi, Gregory A, Dowling, John E
• Format: Journal Article
• Language: English
• Published: United States Soc Neuroscience 01.06.1997; Society for Neuroscience
• Subjects: Animals; Behavior, Animal - physiology; Cell Nucleus - physiology; Color Vision Defects - genetics; Genotype; In Situ Hybridization; Larva - physiology; Mutagenesis - physiology; Retinal Cone Photoreceptor Cells - chemistry; Retinal Cone Photoreceptor Cells - physiology; RNA, Messenger - analysis; Rod Opsins - genetics; Zebrafish - genetics

A red-blind zebrafish mutant, partial optokinetic response b (pob), has been isolated by measuring eye movements of larvae in a three-generation screen for recessive mutations affecting the visual system. pob larvae exhibit eye movements in response to rotating black and white stripes illuminated wi...