Label-free quantitative proteomic analysis of ethanamizuril-resistant versus -sensitive strains of Eimeria tenella

• Published in: Parasites & vectors Vol. 15; no. 1; p. 319
• Main Authors: Cheng, Peipei, Wang, Chunmei, Zhang, Lifang, Fei, Chenzhong, Liu, Yingchun, Wang, Mi, Zhang, Keyu, Wang, Xiaoyang, Gu, Feng, Xue, Feiqun
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 08.09.2022; BioMed Central; BMC
• Subjects: Analysis; Anticoccidial; ATP; birds; Chemotherapy; Coccidiosis; coccidiostats; Drug dosages; Drug resistance; drug therapy; Eimeria tenella; Encyclopaedias; Encyclopedias; Ethanamizuril; gene expression regulation; gene ontology; Genes; genome; Genomes; Label-free proteomics; Laboratories; Methods; Network analysis; oocysts; Parasites; Parasitic diseases; Parasitoses; Peptides; Potassium; Poultry; poultry feed; poultry industry; Production methods; protein-protein interactions; Proteins; Proteomics; Resistance mechanisms; Ribosomal proteins; Sporulation; Transcription; transcription (genetics); Triazenes; Triazine; triazines; China; United States > US

Avian coccidiosis is an important parasitic disease that has serious adverse effects on the global poultry industry. The extensive use of anticoccidial drugs has resulted in an increase in drug resistance. Ethanamizuril (EZL) is a novel triazine with high anticoccidial activity. We compared oocyst p...