TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion

• Published in: International journal of endocrinology Vol. 2020; no. 2020; pp. 1 - 9
• Main Authors: Li, Yanbing, Xiao, Haipeng, Zhang, Quan, Liu, Yujie, Chen, Shuwei, Huang, Yanrui, Cao, Siting, Hong, Shubin, Yin, Yali, Yu, Shuang, Guan, Hongyu
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2020; Hindawi; John Wiley & Sons, Inc; Wiley
• Subjects: Cancer; Carcinoma; Care and treatment; Enzymes; Genes; Immunohistochemistry; Instrument industry; Methylene blue; MicroRNA; Thyroid diseases; Thyroid gland; United States; China

Background. Ten-eleven translocation (TET) enzymes catalyze the oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) promoting demethylation in cells. However, the expression pattern and biologic significance of TET in papillary thyroid carcinoma (PTC) remain unclear. This study aim...