A Review of the Epidemiology, Pathophysiology, and Efficacy of Anti-diabetic Drugs Used in the Treatment of Nonalcoholic Fatty Liver Disease

• Published in: Digestive diseases and sciences Vol. 66; no. 11; pp. 3676 - 3688
• Main Authors: Manka, Paul P., Kaya, Eda, Canbay, Ali, Syn, Wing-Kin
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.11.2021; Springer; Springer Nature B.V
• Subjects: Antidiabetics; Biochemistry; Blood sugar; Comparative analysis; Development and progression; Diabetes; Drug therapy; Epidemiology; Fatty liver; Gastroenterology; Health aspects; Hepatology; Humans; Hypoglycemic agents; Hypoglycemic Agents - therapeutic use; Insulin resistance; Invited Review; Liver diseases; Medicine; Medicine & Public Health; Non-alcoholic Fatty Liver Disease - drug therapy; Oncology; Transplant Surgery; Type 2 diabetes; NAFLD; Diabetes; NASH; Fibrosis

In recent years, epidemiological studies have consistently demonstrated that the coexistence of nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) is strongly associated with increased mortality and morbidity related to hepatic- and extrahepatic causes. Indeed, compared wit...