An influenza A (H1N1) virus, closely related to swine influenza virus, responsible for a fatal case of human influenza

• Published in: Journal of Virology Vol. 68; no. 4; pp. 2051 - 2058
• Main Authors: Wentworth, D.E, Thompson, B.L, Xu, X, Regnery, H.L, Cooley, A.J, McGregor, M.W, Cox, N.J, Hinshaw, V.S
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.04.1994
• Subjects: Acute Disease; Adult; AGGLUTININE; AGLUTININAS; ANIMAL DE LABORATOIRE; ANIMALES DE LABORATORIO; Animals; Base Sequence; Bronchi - microbiology; CERDO; Cross Reactions; GENE; GENERO HUMANO; GENES; Genes, Viral - genetics; Genome, Viral; GENRE HUMAIN; Humans; Infant, Newborn; influenza A virus; Influenza A virus - genetics; Influenza A virus - immunology; Influenza A virus - pathogenicity; Influenza A Virus, H1N1 Subtype; Influenza, Human - epidemiology; Influenza, Human - microbiology; Influenza, Human - mortality; INFLUENZAVIRUS; INFLUENZAVIRUS PORCIN; Male; MAMIFEROS; MAMMIFERE; Maryland - epidemiology; Molecular Sequence Data; Nucleotide Mapping; Pneumonia, Viral - epidemiology; Pneumonia, Viral - microbiology; Pneumonia, Viral - mortality; PORCIN; PROTEINAS; PROTEINE; Respiratory Distress Syndrome, Newborn; RIESGOS OCUPACIONALES; RISQUE PROFESSIONNEL; SECUENCIA NUCLEICA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; SEQUENCE NUCLEIQUE; Swine; VIROSE; VIROSIS; VIRUS; VIRUS DE LA INFLUENZA PORCINA; ZOONOSE; ZOONOSIS; Maryland

In July 1991, an influenza A virus, designated A/Maryland/12/91 (A/MD), was isolated from the bronchial secretions of a 27-year-old animal caretaker. He had been admitted to the hospital with bilateral pneumonia and died of acute respiratory distress syndrome 13 days later. Antigenic analyses with p...