Characterization of hippocampal subfields using ex vivo MRI and histology data: Lessons for in vivo segmentation

• Published in: Hippocampus Vol. 30; no. 6; pp. 545 - 564
• Main Authors: Flores, Robin, Berron, David, Ding, Song‐Lin, Ittyerah, Ranjit, Pluta, John B., Xie, Long, Adler, Daniel H., Robinson, John L., Schuck, Theresa, Trojanowski, John Q., Grossman, Murray, Liu, Weixia, Pickup, Stephen, Das, Sandhitsu R., Wolk, David A., Yushkevich, Paul A., Wisse, Laura E. M.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2020; Wiley Subscription Services, Inc
• Subjects: Aging; Anatomy; Autopsy; Clinical Medicine; Cognition; Dementia disorders; Dentate gyrus; Engineering and Technology; ex vivo; hippocampal subfields; Hippocampus; histology; Image processing; in vivo; Klinisk medicin; Magnetic resonance imaging; Medical and Health Sciences; Medical Engineering; Medical Image Processing; Medical Imaging; Medicin och hälsovetenskap; Medicinsk bildbehandling; Medicinsk bildvetenskap; Medicinteknik; MRI; Radiologi och bildbehandling; Radiology and Medical Imaging; Radiology, Nuclear Medicine and Medical Imaging; Segmentation; Subiculum; Tails; Teknik; segmentation; in vivo; hippocampal subfields; histology; ex vivo; MRI

Hippocampal subfield segmentation on in vivo MRI is of great interest for cognition, aging, and disease research. Extant subfield segmentation protocols have been based on neuroanatomical references, but these references often give limited information on anatomical variability. Moreover, there is ge...