Tumor-on-a-chip: from bioinspired design to biomedical application

• Published in: Microsystems & nanoengineering Vol. 7; no. 1; pp. 50 - 23
• Main Authors: Liu, Xingxing, Fang, Jiaru, Huang, Shuang, Wu, Xiaoxue, Xie, Xi, Wang, Ji, Liu, Fanmao, Zhang, Meng, Peng, Zhenwei, Hu, Ning
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.06.2021; Springer Nature B.V; Nature Publishing Group
• Subjects: 639/925/350/877; 639/925/927/1007; Animal models; Antineoplastic drugs; Antitumor agents; Biology; Biomedical materials; Biomimetics; Cancer; Cancer research; Cancer therapies; Cell culture; Drug screening; Drugs; Engineering; Medical research; Microfluidics; Platforms; Review; Review Article; Reviews; Screening; Structure-function relationships; Tissue culture; Tissue engineering; Tumor microenvironment; Tumors; Microfluidics; Electronic devices

Cancer is one of the leading causes of human death, despite enormous efforts to explore cancer biology and develop anticancer therapies. The main challenges in cancer research are establishing an efficient tumor microenvironment in vitro and exploring efficient means for screening anticancer drugs t...