Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model

• Published in: Journal of neuroinflammation Vol. 12; no. 1; p. 105
• Main Authors: Zuo, Wen-Qi, Hu, Yu-Juan, Yang, Yang, Zhao, Xue-Yan, Zhang, Yuan-Yuan, Kong, Wen, Kong, Wei-Jia
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 29.05.2015; BioMed Central
• Subjects: Analysis; Animals; Animals, Newborn; Apoptosis Regulatory Proteins - metabolism; Beclin-1; Care and treatment; Cell Phone; Cells, Cultured; Disease Models, Animal; DNA Damage - drug effects; Dose-Response Relationship, Drug; Electric waves; Electromagnetic Phenomena; Electromagnetic radiation; Electromagnetic waves; Electromagnetism; Ganglion; Health aspects; In Vitro Techniques; Inflammation; Inflammation - etiology; Inflammation - metabolism; Inflammation - physiopathology; Lipopolysaccharides - adverse effects; Lipopolysaccharides - pharmacology; Microtubule-Associated Proteins - metabolism; Mitogens; Neurons; Neurons - cytology; Neurons - drug effects; Neurons - physiology; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species - metabolism; Risk factors; Spiral Ganglion - cytology; Spiral Ganglion - drug effects; Spiral Ganglion - physiology; Time Factors

With the increasing popularity of mobile phones, the potential hazards of radiofrequency electromagnetic radiation (RF-EMR) on the auditory system remain unclear. Apart from RF-EMR, humans are also exposed to various physical and chemical factors. We established a lipopolysaccharide (LPS)-induced in...