Remote light-controlled intracellular target recognition by photochromic fluorescent glycoprobes

• Published in: Nature communications Vol. 8; no. 1; pp. 987 - 9
• Main Authors: Zhang, Junji, Fu, Youxin, Han, Hai-Hao, Zang, Yi, Li, Jia, He, Xiao-Peng, Feringa, Ben L., Tian, He
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 17.10.2017; Nature Publishing Group; Nature Portfolio
• Subjects: 631/1647/245/2225; 639/638/439; 639/638/92; Conjugation; Fluorescence; Fluorescent indicators; Humanities and Social Sciences; Intracellular; Medical imaging; multidisciplinary; Photochromism; Probes; Science; Science (multidisciplinary); Target recognition

Development of powerful fluorescence imaging probes and techniques sets the basis for the spatiotemporal tracking of cells at different physiological and pathological stages. While current imaging approaches rely on passive probe–analyte interactions, here we develop photochromic fluorescent glycopr...