Migraine and neuroinflammation: the inflammasome perspective
Background Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inf...
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| Published in | Journal of headache and pain Vol. 22; no. 1; pp. 55 - 13 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Milan
Springer Milan
10.06.2021
Springer Nature B.V BMC |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Background
Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain.
Main body
Inflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection.
Conclusion
Neuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine. |
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| AbstractList | Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain.
Inflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection.
Neuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine. BackgroundNeuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain.Main bodyInflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection.ConclusionNeuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine. Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain.BACKGROUNDNeuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain.Inflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection.MAIN BODYInflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection.Neuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine.CONCLUSIONNeuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine. Abstract Background Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain. Main body Inflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection. Conclusion Neuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine. Background Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition, we discuss the limited data of the contribution of inflammasomes to other aspects of migraine pathophysiology, foremost the activation of the trigeminovascular system and thereby the generation of migraine pain. Main body Inflammasomes are signaling multiprotein complexes and key components of the innate immune system. Their activation causes the production of inflammatory cytokines that can stimulate trigeminal neurons and are thus relevant to the generation of migraine pain. The contribution of inflammasome activation to pain signaling has attracted considerable attention in recent years. Nucleotide-binding domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) is the best characterized inflammasome and there is emerging evidence of its role in a variety of inflammatory pain conditions, including migraine. In this review, we discuss, from an inflammasome point of view, cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma, the connection with genetic factors that make the brain vulnerable to CSD, and the relation of the inflammasome with diseases that are co-morbid with migraine, including stroke, epilepsy, and the possible links with COVID-19 infection. Conclusion Neuroinflammatory pathways, specifically those involving inflammasome proteins, seem promising candidates as treatment targets, and perhaps even biomarkers, in migraine. |
| ArticleNumber | 55 |
| Author | Karatas, Hulya Kursun, Oguzhan Yemisci, Muge van den Maagdenberg, Arn M. J. M. |
| Author_xml | – sequence: 1 givenname: Oguzhan orcidid: 0000-0003-3831-4227 surname: Kursun fullname: Kursun, Oguzhan organization: Department of Neurology, City Hospital – sequence: 2 givenname: Muge orcidid: 0000-0002-1528-1998 surname: Yemisci fullname: Yemisci, Muge organization: Institute of Neurological Sciences and Psychiatry, Hacettepe University, Department of Neurology, Faculty of Medicine, Hacettepe University – sequence: 3 givenname: Arn M. J. M. orcidid: 0000-0002-9310-5535 surname: van den Maagdenberg fullname: van den Maagdenberg, Arn M. J. M. organization: Department of Human Genetics, Leiden University Medical Centre, Department of Neurology, Leiden University Medical Centre – sequence: 4 givenname: Hulya orcidid: 0000-0003-4838-6320 surname: Karatas fullname: Karatas, Hulya email: hulyak@hacettepe.edu.tr organization: Institute of Neurological Sciences and Psychiatry, Hacettepe University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34112082$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1097/00004647-200103000-00005 10.3389/fneur.2020.00146 10.1212/NXI.0000000000000109 10.3390/nu11040811 10.1038/nature09663 10.1177/0333102417723568 10.1111/j.1468-2982.2008.01727.x 10.3389/fncel.2014.00216 10.1038/msb.2012.24 10.3389/fimmu.2020.01021 10.1096/fasebj.2020.34.s1.01881 10.1146/annurev-cellbio-101011-155745 10.1016/S1474-4422(18)30322-3 10.1038/jcbfm.2013.242 10.1007/s12035-014-8995-z 10.1002/ana.21779 10.1007/s11302-017-9576-1 10.1016/j.jneuroim.2011.05.013 10.1385/MN:32:1:051 10.1126/science.1231897 10.1016/j.spen.2010.04.005 10.1111/j.1526-4610.2008.01118.x 10.1177/0333102420906835 10.1038/s41583-018-0055-7 10.1177/0333102417702132 10.1038/nm.3893 10.3389/fncel.2019.00073 10.1111/nan.12621 10.1084/jem.20201707 10.1172/JCI200421227 10.1186/s12974-019-1459-7 10.2174/1567202616666181122165540 10.1097/j.pain.0000000000001856 10.1177/0333102417738202 10.1177/0333102419861710 10.1186/1471-2202-13-143 10.1186/s12974-014-0212-5 10.1016/j.cell.2014.04.007 10.1007/s11916-012-0255-1 10.1016/j.neuron.2009.01.027 10.1038/s41582-019-0227-8 10.1093/bja/aew376 10.1523/JNEUROSCI.0511-10.2010 10.15252/emmm.201810248 10.1111/head.13856 10.1523/JNEUROSCI.6440-10.2011 10.1007/s13238-012-2118-2 10.1016/j.virol.2015.08.010 10.1093/brain/awx089 10.1002/cne.23363 10.1016/j.pain.2013.07.021 10.1212/WNL.0000000000004966 10.1016/0022-510X(94)00283-T 10.1126/science.aap8757 10.1016/j.neulet.2017.11.025 10.1097/PR9.0000000000000628 10.1046/j.1468-2982.1993.1304245.x 10.1186/s10194-020-1084-y 10.4049/jimmunol.1402512 10.1177/0271678X19859381 10.1111/head.13998 10.1016/j.bbi.2018.09.001 10.1111/j.1526-4610.2005.05135.x 10.1186/s10194-019-1016-x 10.1038/nrneurol.2013.192 10.1111/j.1526-4637.2009.00791.x 10.1016/j.jneuroim.2017.09.008 10.1093/brain/awx085 10.1111/j.1468-2982.2005.01059.x 10.1038/cddis.2013.326 10.1002/ana.10158 10.2119/molmed.2013.00117 10.1111/head.12150 10.1016/j.bbi.2020.12.009 10.1002/glia.22561 10.1186/s12974-014-0233-0 10.1038/nm.3804 10.1038/nm0202-136 10.1016/j.immuni.2013.05.016 10.1128/IAI.01003-12 10.1086/511652 10.1038/s41380-020-00965-3 10.1093/brain/awu377 10.1136/bmj.311.7004.541 10.1186/s10194-020-01125-2 10.1016/j.bbi.2020.03.011 10.1159/000332205 10.1186/s12974-015-0258-z 10.1177/0333102415580100 10.1093/infdis/jix636 10.1093/rheumatology/kew208 10.1097/01.wco.0000169750.52406.a2 10.1177/0333102415591497 10.1111/j.1526-4610.2006.00337.x 10.1371/journal.pone.0050626 10.1371/journal.pone.0060677 10.1007/s00439-009-0684-z 10.1016/j.neuroscience.2020.01.008 10.1007/s10571-015-0288-1 10.1212/WNL.0000000000007371 10.1186/s12974-015-0239-2 10.1038/s41582-019-0216-y 10.1007/s12035-015-9681-5 10.1111/j.1445-5994.2012.02847.x 10.1038/ncomms4209 10.1177/0271678X16662043 10.1016/j.brainres.2014.04.019 10.1038/nri.2016.58 10.1152/physrev.00034.2015 10.1146/annurev-physiol-030212-183717 10.1016/j.jaut.2018.03.002 10.1038/ng.3598 10.1016/S0896-6273(04)00085-6 10.1375/136905203770326420 10.1186/s10194-017-0729-y 10.1038/ncomms2608 10.1038/nrneurol.2010.178 10.1371/journal.pone.0052394 10.3390/brainsci9070172 10.1007/s11940-018-0526-1 10.1038/cmi.2016.29 10.1038/nri2096 10.1152/physrev.00027.2014 10.5853/jos.2015.01683 10.1016/j.spen.2013.09.002 10.1016/S1474-4422(14)70220-0 10.1016/0013-4694(51)90079-X 10.1111/head.12755 10.1111/j.1468-2982.2008.01793.x 10.1074/jbc.M112.426254 10.1097/j.pain.0000000000001611 10.1016/j.it.2014.02.007 10.1111/head.13053 10.1038/nrn3638 10.1002/jmd2.12017 10.1155/2015/408136 |
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| Keywords | Neuroinflammation Inflammasome Mitochondrial DNA Cortical spreading depolarization Comorbidity Migraine |
| Language | English |
| License | Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
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| References | Pietrobon, Moskowitz (CR10) 2013; 75 Morais, Liu, Qin, Sadhegian, Ay, Yagmur (CR103) 2020; 161 Cornelison, Woodman, Durham (CR104) 2020; 11 Buse, Reed, Fanning, Bostic, Dodick, Schwedt, Munjal, Singh, Lipton (CR107) 2020; 21 (CR1) 2018; 38 Aydin, Demir, Arikanoglu, Bulut, Ilhan (CR15) 2015; 12 Denes, Pinteaux, Rothwell, Allan (CR122) 2011; 32 Voet, Srinivasan, Lamkanfi, van Loo (CR51) 2019; 11 Zhang, Li, Li, Stary, Clark, Xu (CR64) 2016; 117 Gilhus, Deuschl (CR5) 2019; 15 Choudhuri, Cui, Yong, Bowyer, Klein, Welch (CR74) 2002; 51 Rosen (CR88) 2008; 48 Mulder, Van Baal, Gaist, Kallela, Kaprio, Svensson (CR66) 2003; 6 Horng (CR101) 2014; 35 He, Long, Pan, Zhang, Zhang, Zhang, Qin, Chen, Zhou (CR61) 2019; 16 Walsh, Muruve, Power (CR7) 2014; 15 Vollono, Primiano, Della Marca, Losurdo, Servidei (CR94) 2018; 38 Panicker, Kam, Neifert, Hinkle, Mao, Karuppagounder, Wang, Kumar, Pirooznia, Pletnikova, Troncoso, Dawson, Dawson (CR54) 2020; 34 Kullenberg, Lofqvist, Leinonen, Goldbach-Mansky, Olivecrona (CR45) 2016; 55 Noseda, Burstein (CR8) 2013; 154 Cordero, Alcocer-Gomez, Ryffel (CR43) 2018; 91 Thompson, Hakim (CR22) 2005; 32 Heneka, McManus, Latz (CR52) 2018; 19 Wei, Yang, Zheng, Tang, Li (CR97) 2019; 13 Chen, Li, Huang, Wu, Chen, Wan (CR60) 2014; 1566 Tan, Zhang, Tan, Chen, Meng, Jiang, Meng, Li, Sun, Li, Yu, Tan (CR127) 2015; 12 Ghaemi, Sajadian, Khodaie, Lotfinia, Lotfinia, Aghabarari, Khaleghi Ghadiri, Meuth, Gorji (CR28) 2016; 53 Albrecht, Mainero, Ichijo, Ward, Granziera, Zurcher (CR40) 2019; 92 Sparaco, Feleppa, Lipton, Rapoport, Bigal (CR90) 2006; 26 Kim, Seo, Lee, Ha, Choi, Shin (CR112) 2020; 87 Rajamaki, Nordstrom, Nurmi, Akerman, Kovanen, Oorni (CR121) 2013; 288 Uncini, Lodi, Di Muzio, Silvestri, Servidei, Lugaresi (CR89) 1995; 129 Ghaemi, Alizadeh, Babaei, Jafarian, Khaleghi Ghadiri, Meuth, Kovac, Gorji (CR26) 2018; 38 Takizawa, Shibata, Kayama, Toriumi, Ebine, Koh, Shimizu, Suzuki (CR27) 2016; 36 Kossoff, Andermann (CR125) 2010; 17 Lamkanfi, Dixit (CR49) 2012; 28 Rodrigues, de Sa, Ishimoto, Becerra, Oliveira, Almeida (CR136) 2021; 218 Yilmaz, Ozge, Erdal, Edgunlu, Cakmak, Yalin (CR16) 2010; 11 Bolay, Ozge, Uluduz, Baykan (CR131) 2020; 60 Sarchielli, Alberti, Baldi, Coppola, Rossi, Pierguidi, Floridi, Calabresi (CR56) 2006; 46 Elson, Majamaa, Howell, Chinnery (CR85) 2007; 80 Borte, Zwart, Skogholt, Gabrielsen, Thomas, Fritsche (CR93) 2020; 40 Scher, Bigal, Lipton (CR106) 2005; 18 Russell, Olesen (CR71) 1995; 311 Liao, Mogridge (CR118) 2013; 81 Weber, Fraemohs, Dejana (CR82) 2007; 7 Nowodworska, van den Maagdenberg, Nistri, Fabbretti (CR37) 2017; 13 Lombardo, Mazzon, Basile, Cavalli, Bramanti, Nania (CR76) 2019; 9 Fann, Lee, Manzanero, Tang, Gelderblom, Chunduri (CR115) 2013; 4 Ayata, Lauritzen (CR17) 2015; 95 Youm, Nguyen, Grant, Goldberg, Bodogai, Kim, D'Agostino, Planavsky, Lupfer, Kanneganti, Kang, Horvath, Fahmy, Crawford, Biragyn, Alnemri, Dixit (CR63) 2015; 21 Franke, Bieber, Kraft, Weber, Stoll, Schuhmann (CR117) 2021; 92 Edvinsson, Haanes, Warfvinge (CR6) 2019; 15 Hullugundi, Ferrari, van den Maagdenberg, Nistri (CR36) 2013; 8 Broz, Dixit (CR48) 2016; 16 Keddie, Parker, Lachmann, Ginsberg (CR42) 2018; 20 Tottene, Conti, Fabbro, Vecchia, Shapovalova, Santello, van den Maagdenberg, Ferrari, Pietrobon (CR31) 2009; 61 Levy (CR12) 2012; 16 Gross, Klement, Schoenen, D'Agostino, Fischer (CR62) 2019; 11 van den Maagdenberg, Pietrobon, Pizzorusso, Kaja, Broos, Cesetti (CR32) 2004; 41 Russell, Olesen (CR70) 1993; 13 Van Opdenbosch, Gurung, Vande Walle, Fossoul, Kanneganti, Lamkanfi (CR50) 2014; 5 Buse, Loder, Gorman, Stewart, Reed, Fanning, Serrano, Lipton (CR3) 2013; 53 Ceruti, Villa, Fumagalli, Colombo, Magni, Zanardelli, Fabbretti, Verderio, van den Maagdenberg, Nistri, Abbracchio (CR38) 2011; 31 Lu, Kwan, Levine, Olofsson, Yang, Li, Joshi, Wang, Andersson, Chavan, Tracey (CR102) 2014; 20 Lee, Lee, Chung (CR110) 2016; 18 Eikermann-Haerter, Baum, Ferrari, van den Maagdenberg, Moskowitz, Ayata (CR33) 2009; 66 Perini, D'Andrea, Galloni, Pignatelli, Billo, Alba, Bussone, Toso (CR14) 2005; 45 Lemos, Alonso, Barros, Sequeiros, Pereira-Monteiro, Mendonca (CR87) 2012; 7 Jander, Schroeter, Peters, Witte, Stoll (CR73) 2001; 21 de Boer, Terwindt, van den Maagdenberg (CR69) 2020; 21 Leao (CR19) 1951; 3 Yang, Gao, Lu, Wang, Gao, Zhu, Cai, Lai, Yang (CR80) 2015; 12 Zhu, Yan, Geng, Wang, Li, Feng (CR123) 2016; 36 De Corato, Lisi, Capuano, Tringali, Tramutola, Navarra (CR58) 2011; 237 Poh, Kang, Baik, Ng, She, Balaganapathy, Dheen, Magnus, Gelderblom, Sobey, Koo, Fann, Arumugam (CR113) 2019; 75 Takizawa, Qin, Lopes de Morais, Sugimoto, Chung, Morsett (CR25) 2020; 40 Hansen, Christensen, Olesen (CR68) 2017; 18 Yang, Liu, Xiao (CR53) 2017; 14 Zheng, Liu, Zhou, Yan, Chen, Ma (CR83) 2018; 218 Lamkanfi, Dixit (CR47) 2014; 157 de Monasterio-Schrader, Patzig, Mobius, Barrette, Wagner, Kusch (CR79) 2013; 61 Yang, Wang, Wei, Han, Meng, Zhang, Shi, Li, Xin, Pang, Yi (CR114) 2014; 34 Hougaard, Amin, Christensen, Younis, Wolfram, Cramer, Larsson, Ashina (CR30) 2017; 140 Schuh, Lohse, Ertl-Wagner, Witt, Krumbholz, Frankenberger, Gerdes, Hohlfeld, Kümpfel (CR44) 2015; 2 Nieto-Torres, Verdia-Baguena, Jimenez-Guardeno, Regla-Nava, Castano-Rodriguez, Fernandez-Delgado (CR134) 2015; 485 Lenart, Brough, Denes (CR132) 2016; 36 Franceschini, Nair, Bele, van den Maagdenberg, Nistri, Fabbretti (CR35) 2012; 13 Zhou, Yazdi, Menu, Tschopp (CR98) 2011; 469 Mantegazza, Cestele (CR124) 2018; 667 Cao, Zhang, Lu, Wang, Zhang, Sun, Bao, Tian, Ning, Wang, Cui (CR116) 2020; 444 (CR2) 2018; 17 Yue, Wei, Yang, Liu, Yang, Zhang (CR130) 2020; 46 Bolay, Gul, Baykan (CR138) 2020; 60 Munoz-Planillo, Kuffa, Martinez-Colon, Smith, Rajendiran, Nunez (CR120) 2013; 38 Alfonso-Loeches, Urena-Peralta, Morillo-Bargues, Oliver-De La Cruz, Guerri (CR99) 2014; 8 Zaki, Freilinger, Klopstock, Baldwin, Heisner, Adams, Dichgans, Wagler, Boles (CR91) 2009; 29 Loggia, Chonde, Akeju, Arabasz, Catana, Edwards, Hill, Hsu, Izquierdo-Garcia, Ji, Riley, Wasan, Zürcher, Albrecht, Vangel, Rosen, Napadow, Hooker (CR41) 2015; 138 Santoni, Cardinali, Morelli, Santoni, Nabissi, Amantini (CR55) 2015; 12 Gursoy-Ozdemir, Qiu, Matsuoka, Bolay, Bermpohl, Jin, Wang, Rosenberg, Lo, Moskowitz (CR29) 2004; 113 Zhang, Levy, Noseda, Kainz, Jakubowski, Burstein (CR21) 2010; 30 Guo, Callaway, Ting (CR133) 2015; 21 Hawkins, Cornelison, Blankenship, Durham (CR105) 2017; 2 Bruno, Carpino, Carpino, Zicari (CR13) 2007; 11 Brainstorm, Anttila, Bulik-Sullivan, Finucane, Walters, Bras (CR109) 2018; 360 Smeitink, Koene, Beyrath, Saris, Turnbull, Janssen (CR95) 2019; 46 Nomura, So, Tamura, Busso (CR119) 2015; 195 Karatas, Erdener, Gursoy-Ozdemir, Lule, Eren-Kocak, Sen, Dalkara (CR23) 2013; 339 Zhao, Eising, de Vries, Vijfhuizen (CR84) 2016; 36 de Vries, Frants, Ferrari, van den Maagdenberg (CR67) 2009; 126 Franceschini, Vilotti, Ferrari, van den Maagdenberg, Nistri, Fabbretti (CR39) 2013; 8 Gormley, Anttila, Winsvold, Palta, Esko, Pers (CR78) 2016; 48 Bo, Davidsen, Gulbrandsen, Dietrichs, Bovim, Stovner (CR59) 2009; 29 Magni, Boccazzi, Bodini, Abbracchio, van den Maagdenberg, Ceruti (CR34) 2019; 39 Lu, Wang, Andersson, Tracey (CR81) 2013; 4 Shah (CR135) 2020; 11 Eising, Shyti, AC’t Hoen, Vijfhuizen, SMH, LAM (CR75) 2017; 54 Shen, Mao, Yin, Zhang, Jin, Deng (CR129) 2018; 15 Meng, Tan, Tan, Jiang, Tan, Li, Wang, Yu (CR128) 2014; 11 Sutherland, Griffiths (CR108) 2017; 57 Matsuoka, Yamashita, Matsuda, Kawai, Sawa, Amaya (CR65) 2019; 160 Kim, Chen, Andreazza (CR96) 2015; 2015 Messali, Sanderson, Blumenfeld, Goadsby, Buse, Varon (CR4) 2016; 56 Bolay, Reuter, Dunn, Huang, Boas, Moskowitz (CR20) 2002; 8 Ferrari, Klever, Terwindt, Ayata, van den Maagdenberg (CR9) 2015; 14 Lampron, Pimentel-Coelho, Rivest (CR46) 2013; 521 Yorns, Hardison (CR86) 2013; 20 Woodbridge, Liang, Davis, Vandebona, Sue (CR92) 2013; 43 Pelzer, Haan, Stam, Vijfhuizen, Koelewijn, Smagge, de Vries, Ferrari, van den Maagdenberg, Terwindt (CR72) 2018; 90 Vezzani, French, Bartfai, Baram (CR126) 2011; 7 Ribeiro, Oliveira-Giacomelli, Glaser, Arnaud-Sampaio, Andrejew, Dieckmann (CR137) 2021; 26 Oliveira, Bachi, Ribeiro, Mello, Tufik, Peres (CR57) 2017; 313 Charles, Baca (CR18) 2013; 9 Yemisci, Eikermann-Haerter (CR111) 2019; 20 Chen, Qin, Seidel, Zheng, Eikermann, Ferrari, van den Maagdenberg, Moskowitz, Ayata, Eikermann-Haerter (CR24) 2017; 140 Zhong, Zhai, Liang, Mori, Han, Sutterwala, Qiao (CR100) 2013; 4 Goadsby, Holland, Martins-Oliveira, Hoffmann, Schankin, Akerman (CR11) 2017; 97 Wang, Zhang, Yang, Zhu, Stepaniants, Zhang, Meng, Peters, He, Ni, Slipetz, Crackower, Houshyar, Tan, Asante-Appiah, O'Neill, Jane Luo, Thieringer, Yuan, Chiu, Yee Lum, Lamb, Boie, Wilkinson, Schadt, Dai, Roberts (CR77) 2012; 8 IM Wang (1271_CR77) 2012; 8 C Ayata (1271_CR17) 2015; 95 S Alfonso-Loeches (1271_CR99) 2014; 8 A Uncini (1271_CR89) 1995; 129 AM van den Maagdenberg (1271_CR32) 2004; 41 Z Zhong (1271_CR100) 2013; 4 W He (1271_CR61) 2019; 16 JL Hawkins (1271_CR105) 2017; 2 E Schuh (1271_CR44) 2015; 2 R Munoz-Planillo (1271_CR120) 2013; 38 NE Gilhus (1271_CR5) 2019; 15 A Lampron (1271_CR46) 2013; 521 P Gormley (1271_CR78) 2016; 48 IA Yilmaz (1271_CR16) 2010; 11 K Shen (1271_CR129) 2018; 15 PP Bruno (1271_CR13) 2007; 11 N Rosen (1271_CR88) 2008; 48 F Yang (1271_CR114) 2014; 34 Headache Classification Committee of the International Headache Society (IHS) (1271_CR1) 2018; 38 A De Corato (1271_CR58) 2011; 237 T Horng (1271_CR101) 2014; 35 S Voet (1271_CR51) 2019; 11 S Jander (1271_CR73) 2001; 21 SP Chen (1271_CR24) 2017; 140 S Yang (1271_CR80) 2015; 12 N Lenart (1271_CR132) 2016; 36 M Yemisci (1271_CR111) 2019; 20 S Borte (1271_CR93) 2020; 40 H Zhang (1271_CR64) 2016; 117 E Eising (1271_CR75) 2017; 54 TS Rodrigues (1271_CR136) 2021; 218 MJ Lee (1271_CR110) 2016; 18 AC Charles (1271_CR18) 2013; 9 N Pelzer (1271_CR72) 2018; 90 T Takizawa (1271_CR27) 2016; 36 MB Russell (1271_CR70) 1993; 13 H Bolay (1271_CR20) 2002; 8 ML Loggia (1271_CR41) 2015; 138 H Zhao (1271_CR84) 2016; 36 H Guo (1271_CR133) 2015; 21 D Levy (1271_CR12) 2012; 16 R Zhou (1271_CR98) 2011; 469 CS Thompson (1271_CR22) 2005; 32 P Broz (1271_CR48) 2016; 16 M Mantegazza (1271_CR124) 2018; 667 H Karatas (1271_CR23) 2013; 339 L Poh (1271_CR113) 2019; 75 R Noseda (1271_CR8) 2013; 154 Y Gursoy-Ozdemir (1271_CR29) 2004; 113 HK Kim (1271_CR96) 2015; 2015 L Edvinsson (1271_CR6) 2019; 15 XF Meng (1271_CR128) 2014; 11 T Kullenberg (1271_CR45) 2016; 55 EJ Mulder (1271_CR66) 2003; 6 HG Sutherland (1271_CR108) 2017; 57 C Weber (1271_CR82) 2007; 7 M Sparaco (1271_CR90) 2006; 26 H Bolay (1271_CR138) 2020; 60 P Wei (1271_CR97) 2019; 13 CC Tan (1271_CR127) 2015; 12 G Magni (1271_CR34) 2019; 39 A Hougaard (1271_CR30) 2017; 140 M Lamkanfi (1271_CR47) 2014; 157 A Vezzani (1271_CR126) 2011; 7 M Aydin (1271_CR15) 2015; 12 A Nowodworska (1271_CR37) 2017; 13 A Shah (1271_CR135) 2020; 11 YH Youm (1271_CR63) 2015; 21 N Van Opdenbosch (1271_CR50) 2014; 5 A Messali (1271_CR4) 2016; 56 A Franceschini (1271_CR39) 2013; 8 DS Albrecht (1271_CR40) 2019; 92 S Keddie (1271_CR42) 2018; 20 LE Cornelison (1271_CR104) 2020; 11 Y Cao (1271_CR116) 2020; 444 D Pietrobon (1271_CR10) 2013; 75 Y Matsuoka (1271_CR65) 2019; 160 G Santoni (1271_CR55) 2015; 12 F Perini (1271_CR14) 2005; 45 B Lu (1271_CR81) 2013; 4 P de Monasterio-Schrader (1271_CR79) 2013; 61 A Denes (1271_CR122) 2011; 32 KC Liao (1271_CR118) 2013; 81 L Chen (1271_CR60) 2014; 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| References_xml | – volume: 21 start-page: 218 issue: 3 year: 2001 end-page: 225 ident: CR73 article-title: Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-200103000-00005 – volume: 11 start-page: 245 issue: 4 year: 2007 end-page: 248 ident: CR13 article-title: An overview on immune system and migraine publication-title: Eur Rev Med Pharmacol Sci – volume: 11 start-page: 146 year: 2020 ident: CR104 article-title: Inhibition of trigeminal nociception by non-invasive Vagus nerve stimulation: investigating the role of GABAergic and serotonergic pathways in a model of episodic migraine publication-title: Front Neurol doi: 10.3389/fneur.2020.00146 – volume: 2 start-page: e109 issue: 4 year: 2015 ident: CR44 article-title: Expanding spectrum of neurologic manifestations in patients with NLRP3 low-penetrance mutations publication-title: Neurol Neuroimmunol Neuroinflamm doi: 10.1212/NXI.0000000000000109 – volume: 11 start-page: 811 issue: 4 year: 2019 ident: CR62 article-title: Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention publication-title: Nutrients doi: 10.3390/nu11040811 – volume: 469 start-page: 221 issue: 7329 year: 2011 end-page: 225 ident: CR98 article-title: A role for mitochondria in NLRP3 inflammasome activation publication-title: Nature. doi: 10.1038/nature09663 – volume: 38 start-page: 1093 issue: 6 year: 2018 end-page: 1106 ident: CR94 article-title: Migraine in mitochondrial disorders: prevalence and characteristics publication-title: Cephalalgia. doi: 10.1177/0333102417723568 – volume: 29 start-page: 365 issue: 3 year: 2009 end-page: 372 ident: CR59 article-title: Cerebrospinal fluid cytokine levels in migraine, tension-type headache and cervicogenic headache publication-title: Cephalalgia. doi: 10.1111/j.1468-2982.2008.01727.x – volume: 8 start-page: 216 year: 2014 ident: CR99 article-title: Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells publication-title: Front Cell Neurosci doi: 10.3389/fncel.2014.00216 – volume: 8 start-page: 594 issue: 1 year: 2012 ident: CR77 article-title: Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers publication-title: Mol Syst Biol doi: 10.1038/msb.2012.24 – volume: 11 start-page: 1021 year: 2020 ident: CR135 article-title: Novel coronavirus-induced NLRP3 Inflammasome activation: a potential drug target in the treatment of COVID-19 publication-title: Front Immunol doi: 10.3389/fimmu.2020.01021 – volume: 34 start-page: 1 issue: S1 year: 2020 ident: CR54 article-title: NLRP3 inflammasome activation in dopamine neurons contributes to neurodegeneration in Parkinson’s disease publication-title: FASEB J doi: 10.1096/fasebj.2020.34.s1.01881 – volume: 46 start-page: 52 issue: 1 year: 2019 end-page: 62 ident: CR95 article-title: Mitochondrial migraine: disentangling the angiopathy paradigm in m.3243A>G patients publication-title: JIMD Rep – volume: 28 start-page: 137 issue: 1 year: 2012 end-page: 161 ident: CR49 article-title: Inflammasomes and their roles in health and disease publication-title: Annu Rev Cell Dev Biol doi: 10.1146/annurev-cellbio-101011-155745 – volume: 17 start-page: 954 issue: 11 year: 2018 end-page: 976 ident: CR2 article-title: Global, regional, and national burden of migraine and tension-type headache, 1990-2016: a systematic analysis for the global burden of disease study 2016 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(18)30322-3 – volume: 34 start-page: 660 issue: 4 year: 2014 end-page: 667 ident: CR114 article-title: NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2013.242 – volume: 53 start-page: 143 issue: 1 year: 2016 end-page: 154 ident: CR28 article-title: Immunomodulatory effect of toll-like Receptor-3 ligand poly I:C on cortical spreading depression publication-title: Mol Neurobiol doi: 10.1007/s12035-014-8995-z – volume: 66 start-page: 564 issue: 4 year: 2009 end-page: 568 ident: CR33 article-title: Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice publication-title: Ann Neurol doi: 10.1002/ana.21779 – volume: 13 start-page: 511 issue: 4 year: 2017 end-page: 520 ident: CR37 article-title: In situ imaging reveals properties of purinergic signalling in trigeminal sensory ganglia in vitro publication-title: Purinergic Signal doi: 10.1007/s11302-017-9576-1 – volume: 237 start-page: 39 issue: 1–2 year: 2011 end-page: 46 ident: CR58 article-title: Trigeminal satellite cells express functional calcitonin gene-related peptide receptors, whose activation enhances interleukin-1beta pro-inflammatory effects publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2011.05.013 – volume: 32 start-page: 51 issue: 1 year: 2005 end-page: 57 ident: CR22 article-title: Cortical spreading depression modifies components of the inflammatory cascade publication-title: Mol Neurobiol doi: 10.1385/MN:32:1:051 – volume: 339 start-page: 1092 issue: 6123 year: 2013 end-page: 1095 ident: CR23 article-title: Spreading depression triggers headache by activating neuronal Panx1 channels publication-title: Science. doi: 10.1126/science.1231897 – volume: 17 start-page: 117 issue: 2 year: 2010 end-page: 122 ident: CR125 article-title: Migraine and epilepsy publication-title: Semin Pediatr Neurol doi: 10.1016/j.spen.2010.04.005 – volume: 48 start-page: 733 issue: 5 year: 2008 end-page: 734 ident: CR88 article-title: Headache and mitochondrial disorders publication-title: Headache. doi: 10.1111/j.1526-4610.2008.01118.x – volume: 40 start-page: 625 issue: 6 year: 2020 end-page: 634 ident: CR93 article-title: Mitochondrial genome-wide association study of migraine - the HUNT study publication-title: Cephalalgia. doi: 10.1177/0333102420906835 – volume: 19 start-page: 610 issue: 10 year: 2018 end-page: 621 ident: CR52 article-title: Inflammasome signalling in brain function and neurodegenerative disease publication-title: Nat Rev Neurosci doi: 10.1038/s41583-018-0055-7 – volume: 38 start-page: 626 issue: 4 year: 2018 end-page: 638 ident: CR26 article-title: Astrocyte-mediated inflammation in cortical spreading depression publication-title: Cephalalgia. doi: 10.1177/0333102417702132 – volume: 21 start-page: 677 issue: 7 year: 2015 end-page: 687 ident: CR133 article-title: Inflammasomes: mechanism of action, role in disease, and therapeutics publication-title: Nat Med doi: 10.1038/nm.3893 – volume: 13 start-page: 73 year: 2019 ident: CR97 article-title: The potential role of the NLRP3 Inflammasome activation as a link between mitochondria ROS generation and Neuroinflammation in postoperative cognitive dysfunction publication-title: Front Cell Neurosci doi: 10.3389/fncel.2019.00073 – volume: 46 start-page: 770 issue: 7 year: 2020 end-page: 785 ident: CR130 article-title: NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence publication-title: Neuropathol Appl Neurobiol doi: 10.1111/nan.12621 – volume: 218 start-page: e20201707 issue: 3 year: 2021 ident: CR136 article-title: Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients publication-title: J Exp Med doi: 10.1084/jem.20201707 – volume: 113 start-page: 1447 issue: 10 year: 2004 end-page: 1455 ident: CR29 article-title: Cortical spreading depression activates and upregulates MMP-9 publication-title: J Clin Invest doi: 10.1172/JCI200421227 – volume: 16 start-page: 78 issue: 1 year: 2019 ident: CR61 article-title: Microglial NLRP3 inflammasome activation mediates IL-1beta release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model publication-title: J Neuroinflammation doi: 10.1186/s12974-019-1459-7 – volume: 15 start-page: 276 issue: 4 year: 2018 end-page: 281 ident: CR129 article-title: NLRP3 Inflammasome activation leads to epileptic neuronal apoptosis publication-title: Curr Neurovasc Res doi: 10.2174/1567202616666181122165540 – volume: 161 start-page: 1661 issue: 7 year: 2020 end-page: 1669 ident: CR103 article-title: Vagus nerve stimulation inhibits cortical spreading depression exclusively through central mechanisms publication-title: Pain. doi: 10.1097/j.pain.0000000000001856 – volume: 38 start-page: 1 issue: 1 year: 2018 end-page: 211 ident: CR1 article-title: The International Classification of Headache Disorders, 3rd edition publication-title: Cephalalgia doi: 10.1177/0333102417738202 – volume: 39 start-page: 1809 issue: 14 year: 2019 end-page: 1817 ident: CR34 article-title: Basal astrocyte and microglia activation in the central nervous system of familial hemiplegic migraine type I mice publication-title: Cephalalgia. doi: 10.1177/0333102419861710 – volume: 13 start-page: 143 year: 2012 ident: CR35 article-title: Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine publication-title: BMC Neurosci doi: 10.1186/1471-2202-13-143 – volume: 11 start-page: 212 issue: 1 year: 2014 ident: CR128 article-title: Inhibition of the NLRP3 inflammasome provides neuroprotection in rats following amygdala kindling-induced status epilepticus publication-title: J Neuroinflammation doi: 10.1186/s12974-014-0212-5 – volume: 157 start-page: 1013 issue: 5 year: 2014 end-page: 1022 ident: CR47 article-title: Mechanisms and functions of inflammasomes publication-title: Cell. doi: 10.1016/j.cell.2014.04.007 – volume: 16 start-page: 270 issue: 3 year: 2012 end-page: 277 ident: CR12 article-title: Endogenous mechanisms underlying the activation and sensitization of meningeal nociceptors: the role of immuno-vascular interactions and cortical spreading depression publication-title: Curr Pain Headache Rep doi: 10.1007/s11916-012-0255-1 – volume: 61 start-page: 762 issue: 5 year: 2009 end-page: 773 ident: CR31 article-title: Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in ca(v)2.1 knockin migraine mice publication-title: Neuron. doi: 10.1016/j.neuron.2009.01.027 – volume: 15 start-page: 429 issue: 8 year: 2019 end-page: 430 ident: CR5 article-title: Neuroinflammation - a common thread in neurological disorders publication-title: Nat Rev Neurol doi: 10.1038/s41582-019-0227-8 – volume: 117 start-page: 693 issue: 6 year: 2016 end-page: 707 ident: CR64 article-title: The inflammasome as a target for pain therapy publication-title: Br J Anaesth doi: 10.1093/bja/aew376 – volume: 30 start-page: 8807 issue: 26 year: 2010 end-page: 8814 ident: CR21 article-title: Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura publication-title: J Neurosci doi: 10.1523/JNEUROSCI.0511-10.2010 – volume: 11 start-page: e10248 issue: 6 year: 2019 ident: CR51 article-title: Inflammasomes in neuroinflammatory and neurodegenerative diseases publication-title: EMBO Mol Med doi: 10.15252/emmm.201810248 – volume: 60 start-page: 1415 issue: 7 year: 2020 end-page: 1421 ident: CR138 article-title: COVID-19 is a real headache! publication-title: Headache. doi: 10.1111/head.13856 – volume: 31 start-page: 3638 issue: 10 year: 2011 end-page: 3649 ident: CR38 article-title: Calcitonin gene-related peptide-mediated enhancement of purinergic neuron/glia communication by the algogenic factor bradykinin in mouse trigeminal ganglia from wild-type and R192Q Cav2.1 Knock-in mice: implications for basic mechanisms of migraine pain publication-title: J Neurosci doi: 10.1523/JNEUROSCI.6440-10.2011 – volume: 4 start-page: 163 issue: 3 year: 2013 end-page: 167 ident: CR81 article-title: Regulation of HMGB1 release by inflammasomes publication-title: Protein Cell doi: 10.1007/s13238-012-2118-2 – volume: 485 start-page: 330 year: 2015 end-page: 339 ident: CR134 article-title: Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome publication-title: Virology. doi: 10.1016/j.virol.2015.08.010 – volume: 140 start-page: 1633 issue: 6 year: 2017 end-page: 1642 ident: CR30 article-title: Increased brainstem perfusion, but no blood-brain barrier disruption, during attacks of migraine with aura publication-title: Brain. doi: 10.1093/brain/awx089 – volume: 521 start-page: 3863 issue: 17 year: 2013 end-page: 3876 ident: CR46 article-title: Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration publication-title: J Comp Neurol doi: 10.1002/cne.23363 – volume: 154 start-page: S44 issue: Suppl 1 year: 2013 end-page: S53 ident: CR8 article-title: Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain publication-title: Pain. doi: 10.1016/j.pain.2013.07.021 – volume: 90 start-page: e575 issue: 7 year: 2018 end-page: ee82 ident: CR72 article-title: Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation publication-title: Neurology. doi: 10.1212/WNL.0000000000004966 – volume: 129 start-page: 214 issue: 2 year: 1995 end-page: 222 ident: CR89 article-title: Abnormal brain and muscle energy metabolism shown by 31P-MRS in familial hemiplegic migraine publication-title: J Neurol Sci doi: 10.1016/0022-510X(94)00283-T – volume: 360 start-page: eaap8757 issue: 6395 year: 2018 ident: CR109 article-title: Analysis of shared heritability in common disorders of the brain publication-title: Science doi: 10.1126/science.aap8757 – volume: 667 start-page: 92 year: 2018 end-page: 102 ident: CR124 article-title: Pathophysiological mechanisms of migraine and epilepsy: similarities and differences publication-title: Neurosci Lett doi: 10.1016/j.neulet.2017.11.025 – volume: 2 start-page: e628 issue: 6 year: 2017 ident: CR105 article-title: Vagus nerve stimulation inhibits trigeminal nociception in a rodent model of episodic migraine publication-title: Pain Rep doi: 10.1097/PR9.0000000000000628 – volume: 13 start-page: 245 issue: 4 year: 1993 end-page: 248 ident: CR70 article-title: The genetics of migraine without aura and migraine with aura publication-title: Cephalalgia. doi: 10.1046/j.1468-2982.1993.1304245.x – volume: 21 start-page: 23 issue: 1 year: 2020 ident: CR107 article-title: Comorbid and co-occurring conditions in migraine and associated risk of increasing headache pain intensity and headache frequency: results of the migraine in America symptoms and treatment (MAST) study publication-title: J Headache Pain doi: 10.1186/s10194-020-1084-y – volume: 195 start-page: 5718 issue: 12 year: 2015 end-page: 5724 ident: CR119 article-title: Intracellular ATP decrease mediates NLRP3 Inflammasome activation upon Nigericin and crystal stimulation publication-title: J Immunol doi: 10.4049/jimmunol.1402512 – volume: 40 start-page: 1117 issue: 5 year: 2020 end-page: 1131 ident: CR25 article-title: Non-invasively triggered spreading depolarizations induce a rapid pro-inflammatory response in cerebral cortex publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X19859381 – volume: 60 start-page: 2508 issue: 10 year: 2020 end-page: 2521 ident: CR131 article-title: Are migraine patients at increased risk for symptomatic coronavirus disease 2019 due to shared comorbidities? publication-title: Headache. doi: 10.1111/head.13998 – volume: 75 start-page: 34 year: 2019 end-page: 47 ident: CR113 article-title: Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2018.09.001 – volume: 2015 start-page: 408136 year: 2015 ident: CR96 article-title: The potential role of the NLRP3 Inflammasome as a link between mitochondrial complex I dysfunction and inflammation in bipolar disorder publication-title: Neural Plast – volume: 45 start-page: 926 issue: 7 year: 2005 end-page: 931 ident: CR14 article-title: Plasma cytokine levels in migraineurs and controls publication-title: Headache. doi: 10.1111/j.1526-4610.2005.05135.x – volume: 20 start-page: 63 issue: 1 year: 2019 ident: CR111 article-title: Aura and Stroke: relationship and what we have learnt from preclinical models publication-title: J Headache Pain. doi: 10.1186/s10194-019-1016-x – volume: 9 start-page: 637 issue: 11 year: 2013 end-page: 644 ident: CR18 article-title: Cortical spreading depression and migraine publication-title: Nat Rev Neurol doi: 10.1038/nrneurol.2013.192 – volume: 11 start-page: 492 issue: 4 year: 2010 end-page: 497 ident: CR16 article-title: Cytokine polymorphism in patients with migraine: some suggestive clues of migraine and inflammation publication-title: Pain Med doi: 10.1111/j.1526-4637.2009.00791.x – volume: 313 start-page: 138 year: 2017 end-page: 144 ident: CR57 article-title: Unbalanced plasma TNF-alpha and IL-12/IL-10 profile in women with migraine is associated with psychological and physiological outcomes publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2017.09.008 – volume: 140 start-page: 1643 issue: 6 year: 2017 end-page: 1656 ident: CR24 article-title: Inhibition of the P2X7-PANX1 complex suppresses spreading depolarization and neuroinflammation publication-title: Brain. doi: 10.1093/brain/awx085 – volume: 26 start-page: 361 issue: 4 year: 2006 end-page: 372 ident: CR90 article-title: Mitochondrial dysfunction and migraine: evidence and hypotheses publication-title: Cephalalgia. doi: 10.1111/j.1468-2982.2005.01059.x – volume: 4 start-page: e790 year: 2013 ident: CR115 article-title: Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke publication-title: Cell Death Dis doi: 10.1038/cddis.2013.326 – volume: 51 start-page: 499 issue: 4 year: 2002 end-page: 506 ident: CR74 article-title: Cortical spreading depression and gene regulation: relevance to migraine publication-title: Ann Neurol doi: 10.1002/ana.10158 – volume: 20 start-page: 350 issue: 1 year: 2014 end-page: 358 ident: CR102 article-title: alpha7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release publication-title: Mol Med doi: 10.2119/molmed.2013.00117 – volume: 53 start-page: 1278 issue: 8 year: 2013 end-page: 1299 ident: CR3 article-title: Sex differences in the prevalence, symptoms, and associated features of migraine, probable migraine and other severe headache: results of the American Migraine Prevalence and Prevention (AMPP) study publication-title: Headache. doi: 10.1111/head.12150 – volume: 92 start-page: 223 year: 2021 end-page: 233 ident: CR117 article-title: The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2020.12.009 – volume: 61 start-page: 1832 issue: 11 year: 2013 end-page: 1847 ident: CR79 article-title: Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2 publication-title: Glia. doi: 10.1002/glia.22561 – volume: 12 start-page: 18 issue: 1 year: 2015 ident: CR127 article-title: NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model publication-title: J Neuroinflammation doi: 10.1186/s12974-014-0233-0 – volume: 21 start-page: 263 issue: 3 year: 2015 end-page: 269 ident: CR63 article-title: The ketone metabolite beta-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease publication-title: Nat Med doi: 10.1038/nm.3804 – volume: 8 start-page: 136 issue: 2 year: 2002 end-page: 142 ident: CR20 article-title: Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model publication-title: Nat Med doi: 10.1038/nm0202-136 – volume: 38 start-page: 1142 issue: 6 year: 2013 end-page: 1153 ident: CR120 article-title: K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter publication-title: Immunity. doi: 10.1016/j.immuni.2013.05.016 – volume: 81 start-page: 570 issue: 2 year: 2013 end-page: 579 ident: CR118 article-title: Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP publication-title: Infect Immun doi: 10.1128/IAI.01003-12 – volume: 80 start-page: 378 issue: 2 year: 2007 end-page: 382 ident: CR85 article-title: Associating mitochondrial DNA variation with complex traits publication-title: Am J Hum Genet doi: 10.1086/511652 – volume: 26 start-page: 1044 issue: 4 year: 2021 end-page: 1059 ident: CR137 article-title: Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology publication-title: Mol Psychiatry doi: 10.1038/s41380-020-00965-3 – volume: 138 start-page: 604 issue: Pt 3 year: 2015 end-page: 615 ident: CR41 article-title: Evidence for brain glial activation in chronic pain patients publication-title: Brain. doi: 10.1093/brain/awu377 – volume: 311 start-page: 541 issue: 7004 year: 1995 end-page: 544 ident: CR71 article-title: Increased familial risk and evidence of genetic factor in migraine publication-title: BMJ. doi: 10.1136/bmj.311.7004.541 – volume: 21 start-page: 64 issue: 1 year: 2020 ident: CR69 article-title: Genetics of migraine aura: an update publication-title: J Headache Pain. doi: 10.1186/s10194-020-01125-2 – volume: 87 start-page: 765 year: 2020 end-page: 776 ident: CR112 article-title: AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2020.03.011 – volume: 32 start-page: 517 issue: 6 year: 2011 end-page: 527 ident: CR122 article-title: Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target publication-title: Cerebrovasc Dis doi: 10.1159/000332205 – volume: 12 start-page: 33 issue: 1 year: 2015 ident: CR80 article-title: Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death publication-title: J Neuroinflammation doi: 10.1186/s12974-015-0258-z – volume: 36 start-page: 44 issue: 1 year: 2016 end-page: 52 ident: CR27 article-title: Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice publication-title: Cephalalgia. doi: 10.1177/0333102415580100 – volume: 218 start-page: 312 issue: 2 year: 2018 end-page: 323 ident: CR83 article-title: Notch4 negatively regulates the inflammatory response to mycobacterium tuberculosis infection by inhibiting TAK1 activation publication-title: J Infect Dis doi: 10.1093/infdis/jix636 – volume: 55 start-page: 1499 issue: 8 year: 2016 end-page: 1506 ident: CR45 article-title: Long-term safety profile of anakinra in patients with severe cryopyrin-associated periodic syndromes publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/kew208 – volume: 18 start-page: 305 issue: 3 year: 2005 end-page: 310 ident: CR106 article-title: Comorbidity of migraine publication-title: Curr Opin Neurol doi: 10.1097/01.wco.0000169750.52406.a2 – volume: 36 start-page: 648 issue: 7 year: 2016 end-page: 657 ident: CR84 article-title: International headache genetics C, Anttila V, et al. gene-based pleiotropy across migraine with aura and migraine without aura patient groups publication-title: Cephalalgia. doi: 10.1177/0333102415591497 – volume: 46 start-page: 200 issue: 2 year: 2006 end-page: 207 ident: CR56 article-title: Proinflammatory cytokines, adhesion molecules, and lymphocyte integrin expression in the internal jugular blood of migraine patients without aura assessed ictally publication-title: Headache. doi: 10.1111/j.1526-4610.2006.00337.x – volume: 7 start-page: e50626 issue: 11 year: 2012 ident: CR87 article-title: Assessing risk factors for migraine: differences in gender transmission publication-title: PLoS One doi: 10.1371/journal.pone.0050626 – volume: 8 start-page: e60677 issue: 4 year: 2013 ident: CR36 article-title: The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1) publication-title: PLoS One doi: 10.1371/journal.pone.0060677 – volume: 126 start-page: 115 issue: 1 year: 2009 end-page: 132 ident: CR67 article-title: Molecular genetics of migraine publication-title: Hum Genet doi: 10.1007/s00439-009-0684-z – volume: 444 start-page: 106 year: 2020 end-page: 117 ident: CR116 article-title: Overexpression of MicroRNA-9a-5p ameliorates NLRP1 Inflammasome-mediated ischemic injury in rats following ischemic stroke publication-title: Neuroscience. doi: 10.1016/j.neuroscience.2020.01.008 – volume: 36 start-page: 981 issue: 6 year: 2016 end-page: 988 ident: CR123 article-title: A polymorphism within the 3'UTR of NLRP3 is associated with susceptibility for ischemic stroke in Chinese population publication-title: Cell Mol Neurobiol doi: 10.1007/s10571-015-0288-1 – volume: 92 start-page: e2038 issue: 17 year: 2019 end-page: e2e50 ident: CR40 article-title: Imaging of neuroinflammation in migraine with aura: a [(11)C]PBR28 PET/MRI study publication-title: Neurology. doi: 10.1212/WNL.0000000000007371 – volume: 12 start-page: 21 issue: 1 year: 2015 ident: CR55 article-title: Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons publication-title: J Neuroinflammation doi: 10.1186/s12974-015-0239-2 – volume: 15 start-page: 483 issue: 8 year: 2019 end-page: 490 ident: CR6 article-title: Does inflammation have a role in migraine? publication-title: Nat Rev Neurol doi: 10.1038/s41582-019-0216-y – volume: 54 start-page: 2986 issue: 4 year: 2017 end-page: 2996 ident: CR75 article-title: Cortical spreading depression causes unique dysregulation of inflammatory pathways in a transgenic mouse model of migraine publication-title: Mol Neurobiol doi: 10.1007/s12035-015-9681-5 – volume: 43 start-page: 150 issue: 2 year: 2013 end-page: 156 ident: CR92 article-title: POLG mutations in Australian patients with mitochondrial disease publication-title: Intern Med J doi: 10.1111/j.1445-5994.2012.02847.x – volume: 12 start-page: 307 issue: 4 year: 2015 end-page: 312 ident: CR15 article-title: Plasma cytokine levels in Migraineurs during and outside of attacks publication-title: Eur J Gen Med – volume: 5 start-page: 3209 issue: 1 year: 2014 ident: CR50 article-title: Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation publication-title: Nat Commun doi: 10.1038/ncomms4209 – volume: 36 start-page: 1668 issue: 10 year: 2016 end-page: 1685 ident: CR132 article-title: Inflammasomes link vascular disease with neuroinflammation and brain disorders publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X16662043 – volume: 1566 start-page: 1 year: 2014 end-page: 11 ident: CR60 article-title: Chemical stimulation of the intracranial dura activates NALP3 inflammasome in trigeminal ganglia neurons publication-title: Brain Res doi: 10.1016/j.brainres.2014.04.019 – volume: 16 start-page: 407 issue: 7 year: 2016 end-page: 420 ident: CR48 article-title: Inflammasomes: mechanism of assembly, regulation and signalling publication-title: Nat Rev Immunol. doi: 10.1038/nri.2016.58 – volume: 97 start-page: 553 issue: 2 year: 2017 end-page: 622 ident: CR11 article-title: Pathophysiology of migraine: a disorder of sensory processing publication-title: Physiol Rev doi: 10.1152/physrev.00034.2015 – volume: 75 start-page: 365 issue: 1 year: 2013 end-page: 391 ident: CR10 article-title: Pathophysiology of migraine publication-title: Annu Rev Physiol doi: 10.1146/annurev-physiol-030212-183717 – volume: 91 start-page: 13 year: 2018 end-page: 22 ident: CR43 article-title: Gain of function mutation and inflammasome driven diseases in human and mouse models publication-title: J Autoimmun doi: 10.1016/j.jaut.2018.03.002 – volume: 48 start-page: 856 issue: 8 year: 2016 end-page: 866 ident: CR78 article-title: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine publication-title: Nat Genet doi: 10.1038/ng.3598 – volume: 41 start-page: 701 issue: 5 year: 2004 end-page: 710 ident: CR32 article-title: A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression publication-title: Neuron. doi: 10.1016/S0896-6273(04)00085-6 – volume: 6 start-page: 422 issue: 5 year: 2003 end-page: 431 ident: CR66 article-title: Genetic and environmental influences on migraine: a twin study across six countries publication-title: Twin Res doi: 10.1375/136905203770326420 – volume: 18 start-page: 32 issue: 1 year: 2017 ident: CR68 article-title: Family studies to find rare high risk variants in migraine publication-title: J Headache Pain. doi: 10.1186/s10194-017-0729-y – volume: 4 start-page: 1611 issue: 1 year: 2013 ident: CR100 article-title: TRPM2 links oxidative stress to NLRP3 inflammasome activation publication-title: Nat Commun doi: 10.1038/ncomms2608 – volume: 7 start-page: 31 issue: 1 year: 2011 end-page: 40 ident: CR126 article-title: The role of inflammation in epilepsy publication-title: Nat Rev Neurol doi: 10.1038/nrneurol.2010.178 – volume: 8 start-page: e52394 issue: 1 year: 2013 ident: CR39 article-title: TNFalpha levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine publication-title: PLoS One doi: 10.1371/journal.pone.0052394 – volume: 9 start-page: 172 issue: 7 year: 2019 ident: CR76 article-title: Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine publication-title: Brain Sci doi: 10.3390/brainsci9070172 – volume: 20 start-page: 43 issue: 10 year: 2018 ident: CR42 article-title: Cryopyrin-associated periodic fever syndrome and the nervous system publication-title: Curr Treat Options Neurol doi: 10.1007/s11940-018-0526-1 – volume: 14 start-page: 65 issue: 1 year: 2017 end-page: 79 ident: CR53 article-title: Post-translational regulation of inflammasomes publication-title: Cell Mol Immunol doi: 10.1038/cmi.2016.29 – volume: 7 start-page: 467 issue: 6 year: 2007 end-page: 477 ident: CR82 article-title: The role of junctional adhesion molecules in vascular inflammation publication-title: Nat Rev Immunol doi: 10.1038/nri2096 – volume: 95 start-page: 953 issue: 3 year: 2015 end-page: 993 ident: CR17 article-title: Spreading depression, spreading depolarizations, and the cerebral vasculature publication-title: Physiol Rev doi: 10.1152/physrev.00027.2014 – volume: 18 start-page: 146 issue: 2 year: 2016 end-page: 156 ident: CR110 article-title: The migraine-stroke connection publication-title: J Stroke doi: 10.5853/jos.2015.01683 – volume: 20 start-page: 188 issue: 3 year: 2013 end-page: 193 ident: CR86 article-title: Mitochondrial dysfunction in migraine publication-title: Semin Pediatr Neurol doi: 10.1016/j.spen.2013.09.002 – volume: 14 start-page: 65 issue: 1 year: 2015 end-page: 80 ident: CR9 article-title: Migraine pathophysiology: lessons from mouse models and human genetics publication-title: Lancet Neurol doi: 10.1016/S1474-4422(14)70220-0 – volume: 3 start-page: 315 issue: 3 year: 1951 end-page: 321 ident: CR19 article-title: The slow voltage variation of cortical spreading depression of activity publication-title: Electroencephalogr Clin Neurophysiol doi: 10.1016/0013-4694(51)90079-X – volume: 56 start-page: 306 issue: 2 year: 2016 end-page: 322 ident: CR4 article-title: Direct and indirect costs of chronic and episodic migraine in the United States: a web-based survey publication-title: Headache. doi: 10.1111/head.12755 – volume: 29 start-page: 719 issue: 7 year: 2009 end-page: 728 ident: CR91 article-title: Two common mitochondrial DNA polymorphisms are highly associated with migraine headache and cyclic vomiting syndrome publication-title: Cephalalgia. doi: 10.1111/j.1468-2982.2008.01793.x – volume: 288 start-page: 13410 issue: 19 year: 2013 end-page: 13419 ident: CR121 article-title: Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome publication-title: J Biol Chem doi: 10.1074/jbc.M112.426254 – volume: 160 start-page: 2149 issue: 9 year: 2019 end-page: 2160 ident: CR65 article-title: NLRP2 inflammasome in dorsal root ganglion as a novel molecular platform that produces inflammatory pain hypersensitivity publication-title: Pain. doi: 10.1097/j.pain.0000000000001611 – volume: 35 start-page: 253 issue: 6 year: 2014 end-page: 261 ident: CR101 article-title: Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome publication-title: Trends Immunol doi: 10.1016/j.it.2014.02.007 – volume: 57 start-page: 537 issue: 4 year: 2017 end-page: 569 ident: CR108 article-title: Genetics of migraine: insights into the molecular basis of migraine disorders publication-title: Headache. doi: 10.1111/head.13053 – volume: 15 start-page: 84 issue: 2 year: 2014 end-page: 97 ident: CR7 article-title: Inflammasomes in the CNS publication-title: Nat Rev Neurosci doi: 10.1038/nrn3638 – volume: 20 start-page: 188 issue: 3 year: 2013 ident: 1271_CR86 publication-title: Semin Pediatr Neurol doi: 10.1016/j.spen.2013.09.002 – volume: 29 start-page: 365 issue: 3 year: 2009 ident: 1271_CR59 publication-title: Cephalalgia. doi: 10.1111/j.1468-2982.2008.01727.x – volume: 80 start-page: 378 issue: 2 year: 2007 ident: 1271_CR85 publication-title: Am J Hum Genet doi: 10.1086/511652 – volume: 11 start-page: 245 issue: 4 year: 2007 ident: 1271_CR13 publication-title: Eur Rev Med Pharmacol Sci – volume: 195 start-page: 5718 issue: 12 year: 2015 ident: 1271_CR119 publication-title: J Immunol doi: 10.4049/jimmunol.1402512 – volume: 54 start-page: 2986 issue: 4 year: 2017 ident: 1271_CR75 publication-title: Mol Neurobiol doi: 10.1007/s12035-015-9681-5 – volume: 48 start-page: 856 issue: 8 year: 2016 ident: 1271_CR78 publication-title: Nat Genet doi: 10.1038/ng.3598 – volume: 12 start-page: 21 issue: 1 year: 2015 ident: 1271_CR55 publication-title: J Neuroinflammation doi: 10.1186/s12974-015-0239-2 – volume: 92 start-page: 223 year: 2021 ident: 1271_CR117 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2020.12.009 – volume: 21 start-page: 677 issue: 7 year: 2015 ident: 1271_CR133 publication-title: Nat Med doi: 10.1038/nm.3893 – volume: 38 start-page: 626 issue: 4 year: 2018 ident: 1271_CR26 publication-title: Cephalalgia. doi: 10.1177/0333102417702132 – volume: 16 start-page: 270 issue: 3 year: 2012 ident: 1271_CR12 publication-title: Curr Pain Headache Rep doi: 10.1007/s11916-012-0255-1 – volume: 12 start-page: 307 issue: 4 year: 2015 ident: 1271_CR15 publication-title: Eur J Gen Med – volume: 485 start-page: 330 year: 2015 ident: 1271_CR134 publication-title: Virology. doi: 10.1016/j.virol.2015.08.010 – volume: 13 start-page: 245 issue: 4 year: 1993 ident: 1271_CR70 publication-title: Cephalalgia. doi: 10.1046/j.1468-2982.1993.1304245.x – volume: 29 start-page: 719 issue: 7 year: 2009 ident: 1271_CR91 publication-title: Cephalalgia. doi: 10.1111/j.1468-2982.2008.01793.x – volume: 218 start-page: 312 issue: 2 year: 2018 ident: 1271_CR83 publication-title: J Infect Dis doi: 10.1093/infdis/jix636 – volume: 311 start-page: 541 issue: 7004 year: 1995 ident: 1271_CR71 publication-title: BMJ. doi: 10.1136/bmj.311.7004.541 – volume: 43 start-page: 150 issue: 2 year: 2013 ident: 1271_CR92 publication-title: Intern Med J doi: 10.1111/j.1445-5994.2012.02847.x – volume: 8 start-page: 136 issue: 2 year: 2002 ident: 1271_CR20 publication-title: Nat Med doi: 10.1038/nm0202-136 – volume: 7 start-page: 31 issue: 1 year: 2011 ident: 1271_CR126 publication-title: Nat Rev Neurol doi: 10.1038/nrneurol.2010.178 – volume: 75 start-page: 365 issue: 1 year: 2013 ident: 1271_CR10 publication-title: Annu Rev Physiol doi: 10.1146/annurev-physiol-030212-183717 – volume: 66 start-page: 564 issue: 4 year: 2009 ident: 1271_CR33 publication-title: Ann Neurol doi: 10.1002/ana.21779 – volume: 12 start-page: 33 issue: 1 year: 2015 ident: 1271_CR80 publication-title: J Neuroinflammation doi: 10.1186/s12974-015-0258-z – volume: 113 start-page: 1447 issue: 10 year: 2004 ident: 1271_CR29 publication-title: J Clin Invest doi: 10.1172/JCI200421227 – volume: 36 start-page: 648 issue: 7 year: 2016 ident: 1271_CR84 publication-title: Cephalalgia. doi: 10.1177/0333102415591497 – volume: 444 start-page: 106 year: 2020 ident: 1271_CR116 publication-title: Neuroscience. doi: 10.1016/j.neuroscience.2020.01.008 – volume: 11 start-page: e10248 issue: 6 year: 2019 ident: 1271_CR51 publication-title: EMBO Mol Med doi: 10.15252/emmm.201810248 – volume: 46 start-page: 52 issue: 1 year: 2019 ident: 1271_CR95 publication-title: JIMD Rep doi: 10.1002/jmd2.12017 – volume: 6 start-page: 422 issue: 5 year: 2003 ident: 1271_CR66 publication-title: Twin Res doi: 10.1375/136905203770326420 – volume: 53 start-page: 143 issue: 1 year: 2016 ident: 1271_CR28 publication-title: Mol Neurobiol doi: 10.1007/s12035-014-8995-z – volume: 8 start-page: 216 year: 2014 ident: 1271_CR99 publication-title: Front Cell Neurosci doi: 10.3389/fncel.2014.00216 – volume: 18 start-page: 32 issue: 1 year: 2017 ident: 1271_CR68 publication-title: J Headache Pain. doi: 10.1186/s10194-017-0729-y – volume: 4 start-page: 1611 issue: 1 year: 2013 ident: 1271_CR100 publication-title: Nat Commun doi: 10.1038/ncomms2608 – volume: 31 start-page: 3638 issue: 10 year: 2011 ident: 1271_CR38 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.6440-10.2011 – volume: 20 start-page: 43 issue: 10 year: 2018 ident: 1271_CR42 publication-title: Curr Treat Options Neurol doi: 10.1007/s11940-018-0526-1 – volume: 1566 start-page: 1 year: 2014 ident: 1271_CR60 publication-title: Brain Res doi: 10.1016/j.brainres.2014.04.019 – volume: 46 start-page: 200 issue: 2 year: 2006 ident: 1271_CR56 publication-title: Headache. doi: 10.1111/j.1526-4610.2006.00337.x – volume: 75 start-page: 34 year: 2019 ident: 1271_CR113 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2018.09.001 – volume: 11 start-page: 811 issue: 4 year: 2019 ident: 1271_CR62 publication-title: Nutrients doi: 10.3390/nu11040811 – volume: 8 start-page: 594 issue: 1 year: 2012 ident: 1271_CR77 publication-title: Mol Syst Biol doi: 10.1038/msb.2012.24 – volume: 30 start-page: 8807 issue: 26 year: 2010 ident: 1271_CR21 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.0511-10.2010 – volume: 12 start-page: 18 issue: 1 year: 2015 ident: 1271_CR127 publication-title: J Neuroinflammation doi: 10.1186/s12974-014-0233-0 – volume: 8 start-page: e52394 issue: 1 year: 2013 ident: 1271_CR39 publication-title: PLoS One doi: 10.1371/journal.pone.0052394 – volume: 19 start-page: 610 issue: 10 year: 2018 ident: 1271_CR52 publication-title: Nat Rev Neurosci doi: 10.1038/s41583-018-0055-7 – volume: 15 start-page: 483 issue: 8 year: 2019 ident: 1271_CR6 publication-title: Nat Rev Neurol doi: 10.1038/s41582-019-0216-y – volume: 39 start-page: 1809 issue: 14 year: 2019 ident: 1271_CR34 publication-title: Cephalalgia. doi: 10.1177/0333102419861710 – volume: 14 start-page: 65 issue: 1 year: 2015 ident: 1271_CR9 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(14)70220-0 – volume: 154 start-page: S44 issue: Suppl 1 year: 2013 ident: 1271_CR8 publication-title: Pain. doi: 10.1016/j.pain.2013.07.021 – volume: 13 start-page: 511 issue: 4 year: 2017 ident: 1271_CR37 publication-title: Purinergic Signal doi: 10.1007/s11302-017-9576-1 – volume: 469 start-page: 221 issue: 7329 year: 2011 ident: 1271_CR98 publication-title: Nature. doi: 10.1038/nature09663 – volume: 32 start-page: 51 issue: 1 year: 2005 ident: 1271_CR22 publication-title: Mol Neurobiol doi: 10.1385/MN:32:1:051 – volume: 11 start-page: 146 year: 2020 ident: 1271_CR104 publication-title: Front Neurol doi: 10.3389/fneur.2020.00146 – volume: 4 start-page: e790 year: 2013 ident: 1271_CR115 publication-title: Cell Death Dis doi: 10.1038/cddis.2013.326 – volume: 87 start-page: 765 year: 2020 ident: 1271_CR112 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2020.03.011 – volume: 57 start-page: 537 issue: 4 year: 2017 ident: 1271_CR108 publication-title: Headache. doi: 10.1111/head.13053 – volume: 15 start-page: 429 issue: 8 year: 2019 ident: 1271_CR5 publication-title: Nat Rev Neurol doi: 10.1038/s41582-019-0227-8 – volume: 161 start-page: 1661 issue: 7 year: 2020 ident: 1271_CR103 publication-title: Pain. doi: 10.1097/j.pain.0000000000001856 – volume: 126 start-page: 115 issue: 1 year: 2009 ident: 1271_CR67 publication-title: Hum Genet doi: 10.1007/s00439-009-0684-z – volume: 26 start-page: 361 issue: 4 year: 2006 ident: 1271_CR90 publication-title: Cephalalgia. doi: 10.1111/j.1468-2982.2005.01059.x – volume: 9 start-page: 637 issue: 11 year: 2013 ident: 1271_CR18 publication-title: Nat Rev Neurol doi: 10.1038/nrneurol.2013.192 – volume: 21 start-page: 263 issue: 3 year: 2015 ident: 1271_CR63 publication-title: Nat Med doi: 10.1038/nm.3804 – volume: 46 start-page: 770 issue: 7 year: 2020 ident: 1271_CR130 publication-title: Neuropathol Appl Neurobiol doi: 10.1111/nan.12621 – volume: 140 start-page: 1633 issue: 6 year: 2017 ident: 1271_CR30 publication-title: Brain. doi: 10.1093/brain/awx089 – volume: 21 start-page: 23 issue: 1 year: 2020 ident: 1271_CR107 publication-title: J Headache Pain doi: 10.1186/s10194-020-1084-y – volume: 60 start-page: 1415 issue: 7 year: 2020 ident: 1271_CR138 publication-title: Headache. doi: 10.1111/head.13856 – volume: 61 start-page: 1832 issue: 11 year: 2013 ident: 1271_CR79 publication-title: Glia. doi: 10.1002/glia.22561 – volume: 61 start-page: 762 issue: 5 year: 2009 ident: 1271_CR31 publication-title: Neuron. doi: 10.1016/j.neuron.2009.01.027 – volume: 521 start-page: 3863 issue: 17 year: 2013 ident: 1271_CR46 publication-title: J Comp Neurol doi: 10.1002/cne.23363 – volume: 4 start-page: 163 issue: 3 year: 2013 ident: 1271_CR81 publication-title: Protein Cell doi: 10.1007/s13238-012-2118-2 – volume: 13 start-page: 73 year: 2019 ident: 1271_CR97 publication-title: Front Cell Neurosci doi: 10.3389/fncel.2019.00073 – volume: 45 start-page: 926 issue: 7 year: 2005 ident: 1271_CR14 publication-title: Headache. doi: 10.1111/j.1526-4610.2005.05135.x – volume: 7 start-page: e50626 issue: 11 year: 2012 ident: 1271_CR87 publication-title: PLoS One doi: 10.1371/journal.pone.0050626 – volume: 56 start-page: 306 issue: 2 year: 2016 ident: 1271_CR4 publication-title: Headache. doi: 10.1111/head.12755 – volume: 36 start-page: 981 issue: 6 year: 2016 ident: 1271_CR123 publication-title: Cell Mol Neurobiol doi: 10.1007/s10571-015-0288-1 – volume: 51 start-page: 499 issue: 4 year: 2002 ident: 1271_CR74 publication-title: Ann Neurol doi: 10.1002/ana.10158 – volume: 36 start-page: 1668 issue: 10 year: 2016 ident: 1271_CR132 publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X16662043 – volume: 97 start-page: 553 issue: 2 year: 2017 ident: 1271_CR11 publication-title: Physiol Rev doi: 10.1152/physrev.00034.2015 – volume: 3 start-page: 315 issue: 3 year: 1951 ident: 1271_CR19 publication-title: Electroencephalogr Clin Neurophysiol doi: 10.1016/0013-4694(51)90079-X – volume: 38 start-page: 1142 issue: 6 year: 2013 ident: 1271_CR120 publication-title: Immunity. doi: 10.1016/j.immuni.2013.05.016 – volume: 15 start-page: 84 issue: 2 year: 2014 ident: 1271_CR7 publication-title: Nat Rev Neurosci doi: 10.1038/nrn3638 – volume: 288 start-page: 13410 issue: 19 year: 2013 ident: 1271_CR121 publication-title: J Biol Chem doi: 10.1074/jbc.M112.426254 – volume: 34 start-page: 1 issue: S1 year: 2020 ident: 1271_CR54 publication-title: FASEB J doi: 10.1096/fasebj.2020.34.s1.01881 – volume: 160 start-page: 2149 issue: 9 year: 2019 ident: 1271_CR65 publication-title: Pain. doi: 10.1097/j.pain.0000000000001611 – volume: 667 start-page: 92 year: 2018 ident: 1271_CR124 publication-title: Neurosci Lett doi: 10.1016/j.neulet.2017.11.025 – volume: 16 start-page: 78 issue: 1 year: 2019 ident: 1271_CR61 publication-title: J Neuroinflammation doi: 10.1186/s12974-019-1459-7 – volume: 18 start-page: 146 issue: 2 year: 2016 ident: 1271_CR110 publication-title: J Stroke doi: 10.5853/jos.2015.01683 – volume: 129 start-page: 214 issue: 2 year: 1995 ident: 1271_CR89 publication-title: J Neurol Sci doi: 10.1016/0022-510X(94)00283-T – volume: 11 start-page: 212 issue: 1 year: 2014 ident: 1271_CR128 publication-title: J Neuroinflammation doi: 10.1186/s12974-014-0212-5 – volume: 40 start-page: 625 issue: 6 year: 2020 ident: 1271_CR93 publication-title: Cephalalgia. doi: 10.1177/0333102420906835 – volume: 34 start-page: 660 issue: 4 year: 2014 ident: 1271_CR114 publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.2013.242 – volume: 237 start-page: 39 issue: 1–2 year: 2011 ident: 1271_CR58 publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2011.05.013 – volume: 17 start-page: 954 issue: 11 year: 2018 ident: 1271_CR2 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(18)30322-3 – volume: 11 start-page: 1021 year: 2020 ident: 1271_CR135 publication-title: Front Immunol doi: 10.3389/fimmu.2020.01021 – volume: 40 start-page: 1117 issue: 5 year: 2020 ident: 1271_CR25 publication-title: J Cereb Blood Flow Metab doi: 10.1177/0271678X19859381 – volume: 138 start-page: 604 issue: Pt 3 year: 2015 ident: 1271_CR41 publication-title: Brain. doi: 10.1093/brain/awu377 – volume: 140 start-page: 1643 issue: 6 year: 2017 ident: 1271_CR24 publication-title: Brain. doi: 10.1093/brain/awx085 – volume: 41 start-page: 701 issue: 5 year: 2004 ident: 1271_CR32 publication-title: Neuron. doi: 10.1016/S0896-6273(04)00085-6 – volume: 21 start-page: 218 issue: 3 year: 2001 ident: 1271_CR73 publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-200103000-00005 – volume: 91 start-page: 13 year: 2018 ident: 1271_CR43 publication-title: J Autoimmun doi: 10.1016/j.jaut.2018.03.002 – volume: 81 start-page: 570 issue: 2 year: 2013 ident: 1271_CR118 publication-title: Infect Immun doi: 10.1128/IAI.01003-12 – volume: 53 start-page: 1278 issue: 8 year: 2013 ident: 1271_CR3 publication-title: Headache. doi: 10.1111/head.12150 – volume: 17 start-page: 117 issue: 2 year: 2010 ident: 1271_CR125 publication-title: Semin Pediatr Neurol doi: 10.1016/j.spen.2010.04.005 – volume: 11 start-page: 492 issue: 4 year: 2010 ident: 1271_CR16 publication-title: Pain Med doi: 10.1111/j.1526-4637.2009.00791.x – volume: 90 start-page: e575 issue: 7 year: 2018 ident: 1271_CR72 publication-title: Neurology. doi: 10.1212/WNL.0000000000004966 – volume: 35 start-page: 253 issue: 6 year: 2014 ident: 1271_CR101 publication-title: Trends Immunol doi: 10.1016/j.it.2014.02.007 – volume: 38 start-page: 1 issue: 1 year: 2018 ident: 1271_CR1 publication-title: Cephalalgia doi: 10.1177/0333102417738202 – volume: 14 start-page: 65 issue: 1 year: 2017 ident: 1271_CR53 publication-title: Cell Mol Immunol doi: 10.1038/cmi.2016.29 – volume: 9 start-page: 172 issue: 7 year: 2019 ident: 1271_CR76 publication-title: Brain Sci doi: 10.3390/brainsci9070172 – volume: 18 start-page: 305 issue: 3 year: 2005 ident: 1271_CR106 publication-title: Curr Opin Neurol doi: 10.1097/01.wco.0000169750.52406.a2 – volume: 55 start-page: 1499 issue: 8 year: 2016 ident: 1271_CR45 publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/kew208 – volume: 313 start-page: 138 year: 2017 ident: 1271_CR57 publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2017.09.008 – volume: 38 start-page: 1093 issue: 6 year: 2018 ident: 1271_CR94 publication-title: Cephalalgia. doi: 10.1177/0333102417723568 – volume: 218 start-page: e20201707 issue: 3 year: 2021 ident: 1271_CR136 publication-title: J Exp Med doi: 10.1084/jem.20201707 – volume: 15 start-page: 276 issue: 4 year: 2018 ident: 1271_CR129 publication-title: Curr Neurovasc Res doi: 10.2174/1567202616666181122165540 – volume: 26 start-page: 1044 issue: 4 year: 2021 ident: 1271_CR137 publication-title: Mol Psychiatry doi: 10.1038/s41380-020-00965-3 – volume: 48 start-page: 733 issue: 5 year: 2008 ident: 1271_CR88 publication-title: Headache. doi: 10.1111/j.1526-4610.2008.01118.x – volume: 8 start-page: e60677 issue: 4 year: 2013 ident: 1271_CR36 publication-title: PLoS One doi: 10.1371/journal.pone.0060677 – volume: 339 start-page: 1092 issue: 6123 year: 2013 ident: 1271_CR23 publication-title: Science. doi: 10.1126/science.1231897 – volume: 92 start-page: e2038 issue: 17 year: 2019 ident: 1271_CR40 publication-title: Neurology. doi: 10.1212/WNL.0000000000007371 – volume: 2 start-page: e109 issue: 4 year: 2015 ident: 1271_CR44 publication-title: Neurol Neuroimmunol Neuroinflamm doi: 10.1212/NXI.0000000000000109 – volume: 95 start-page: 953 issue: 3 year: 2015 ident: 1271_CR17 publication-title: Physiol Rev doi: 10.1152/physrev.00027.2014 – volume: 16 start-page: 407 issue: 7 year: 2016 ident: 1271_CR48 publication-title: Nat Rev Immunol. doi: 10.1038/nri.2016.58 – volume: 2015 start-page: 408136 year: 2015 ident: 1271_CR96 publication-title: Neural Plast doi: 10.1155/2015/408136 – volume: 32 start-page: 517 issue: 6 year: 2011 ident: 1271_CR122 publication-title: Cerebrovasc Dis doi: 10.1159/000332205 – volume: 36 start-page: 44 issue: 1 year: 2016 ident: 1271_CR27 publication-title: Cephalalgia. doi: 10.1177/0333102415580100 – volume: 28 start-page: 137 issue: 1 year: 2012 ident: 1271_CR49 publication-title: Annu Rev Cell Dev Biol doi: 10.1146/annurev-cellbio-101011-155745 – volume: 7 start-page: 467 issue: 6 year: 2007 ident: 1271_CR82 publication-title: Nat Rev Immunol doi: 10.1038/nri2096 – volume: 13 start-page: 143 year: 2012 ident: 1271_CR35 publication-title: BMC Neurosci doi: 10.1186/1471-2202-13-143 – volume: 20 start-page: 63 issue: 1 year: 2019 ident: 1271_CR111 publication-title: J Headache Pain. doi: 10.1186/s10194-019-1016-x – volume: 20 start-page: 350 issue: 1 year: 2014 ident: 1271_CR102 publication-title: Mol Med doi: 10.2119/molmed.2013.00117 – volume: 2 start-page: e628 issue: 6 year: 2017 ident: 1271_CR105 publication-title: Pain Rep doi: 10.1097/PR9.0000000000000628 – volume: 60 start-page: 2508 issue: 10 year: 2020 ident: 1271_CR131 publication-title: Headache. doi: 10.1111/head.13998 – volume: 117 start-page: 693 issue: 6 year: 2016 ident: 1271_CR64 publication-title: Br J Anaesth doi: 10.1093/bja/aew376 – volume: 5 start-page: 3209 issue: 1 year: 2014 ident: 1271_CR50 publication-title: Nat Commun doi: 10.1038/ncomms4209 – volume: 157 start-page: 1013 issue: 5 year: 2014 ident: 1271_CR47 publication-title: Cell. doi: 10.1016/j.cell.2014.04.007 – volume: 21 start-page: 64 issue: 1 year: 2020 ident: 1271_CR69 publication-title: J Headache Pain. doi: 10.1186/s10194-020-01125-2 – volume: 360 start-page: eaap8757 issue: 6395 year: 2018 ident: 1271_CR109 publication-title: Science doi: 10.1126/science.aap8757 |
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Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this... Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this review is to... BackgroundNeuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim of this... Abstract Background Neuroinflammation has an important role in the pathophysiology of migraine, which is a complex neuro-glio-vascular disorder. The main aim... |
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| SubjectTerms | Comorbidity Cortical spreading depolarization COVID-19 Cytokines Depolarization Epilepsy Genetic factors Headache Humans Immune system Inflammasome Inflammasomes Inflammation Innate immunity Internal Medicine Medicine Medicine & Public Health Migraine Migraine Disorders Mitochondrial DNA Neuroinflammation Neurology NLR Family, Pyrin Domain-Containing 3 Protein Pain Pain Medicine Parenchyma Pathophysiology Pyrin protein Review Review Article SARS-CoV-2 Spreading depression Translational Research in Headache |
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| Title | Migraine and neuroinflammation: the inflammasome perspective |
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