Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis - Pfisterer, Ulrich; Petukhov, Viktor; Demharter, Samuel; Meichsner, Johanna; Thompson, Jonatan J.; Batiuk, Mykhailo Y.; Asenjo-Martinez, Andrea; Vasistha, Navneet A.; Thakur, Ashish; Mikkelsen, Jens; Adorjan, Istvan; Pinborg, Lars H.; et al. (Nature communications, 2020)
Keywords: 14/32; 38/91; 631/378/1689/178; 631/378/340; 631/61/514/1949; Adolescent; Adult; Biopsy; Case-Control Studies; Cell Nucleus - genetics; Cell Nucleus - metabolism; Circuits; Datasets as Topic; Drug Resistant Epilepsy - diagnosis; Drug Resistant Epilepsy - genetics; Drug Resistant Epilepsy - pathology; Drug Resistant Epilepsy - surgery; Epilepsy; Epilepsy, Temporal Lobe - diagnosis; Epilepsy, Temporal Lobe - genetics; Epilepsy, Temporal Lobe - pathology; Epilepsy, Temporal Lobe - surgery; Female; Gene expression; Genes; Glutamate receptors; Glutamic Acid - metabolism; Human performance; Humanities and Social Sciences; Humans; Interneurons; Magnetic Resonance Imaging; Male; Microdissection; Middle Aged; Models, Genetic; multidisciplinary; Nerve Net - metabolism; Nerve Net - pathology; Neural coding; Neurological diseases; Neurons - cytology; Neurons - metabolism; Neurons - pathology; Pathophysiology; Phenotypes; Receptors; Receptors, AMPA - genetics; Receptors, AMPA - metabolism; Receptors, Glutamate - genetics; Receptors, Glutamate - metabolism; RNA-Seq; Science; Science (multidisciplinary); Seizures; Signal Transduction - genetics; Single-Cell Analysis; Temporal lobe; Temporal Lobe - cytology; Temporal Lobe - diagnostic imaging; Temporal Lobe - pathology; Temporal Lobe - surgery; Transcription; Transcription, Genetic; Transcriptome - genetics; Up-Regulation; Young Adult; α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors; γ-Aminobutyric acid