Developing a Set of Core Outcomes for Trials in Hemodialysis: An International Delphi Survey

• Published in: American journal of kidney diseases Vol. 70; no. 4; pp. 464 - 475
• Main Authors: Evangelidis, Nicole, Tong, Allison, Manns, Braden, Hemmelgarn, Brenda, Wheeler, David C., Tugwell, Peter, Crowe, Sally, Harris, Tess, Van Biesen, Wim, Winkelmayer, Wolfgang C., Sautenet, Benedicte, O’Donoghue, Donal, Tam-Tham, Helen, Youssouf, Sajeda, Mandayam, Sreedhar, Ju, Angela, Hawley, Carmel, Pollock, Carol, Harris, David C., Johnson, David W., Rifkin, Dena E., Tentori, Francesca, Agar, John, Polkinghorne, Kevan R., Gallagher, Martin, Kerr, Peter G., McDonald, Stephen P., Howard, Kirsten, Howell, Martin, Craig, Jonathan C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2017; Elsevier
• Subjects: Adolescent; Adult; Aged; biochemical end point; cardiovascular disease (CVD); Clinical Trials as Topic; core outcome set; Delphi survey; Delphi Technique; dialysis adequacy; Female; Hemodialysis (HD); Humans; International Cooperation; Life Sciences; lifestyle-related outcomes; Male; Middle Aged; mortality; Nephrology; Outcome Assessment (Health Care) - standards; outcome domains; outcomes; patient-centered care; quality of life; Renal Dialysis; research priorities; Standardized Outcomes in Nephrology-Hemodialysis (SONG-HD); surrogate end points; trials; vascular access problems; well-being; Young Adult; Delphi survey; well-being; surrogate end points; Standardized Outcomes in Nephrology-Hemodialysis (SONG-HD); core outcome set; research priorities; vascular access problems; Hemodialysis (HD); outcome domains; lifestyle-related outcomes; trials; patient-centered care; outcomes; mortality; quality of life; dialysis adequacy; cardiovascular disease (CVD); biochemical end point; Humans; Middle Aged; Male; Outcome Assessment; Young Adult; Delphi Technique; Adult; Female; Clinical Trials as Topic; International Cooperation; Health Care; Adolescent; Aged; Renal Dialysis

Survival and quality of life for patients on hemodialysis therapy remain poor despite substantial research efforts. Existing trials often report surrogate outcomes that may not be relevant to patients and clinicians. The aim of this project was to generate a consensus-based prioritized list of core...