Comparison of oral metabolome profiles of stimulated saliva, unstimulated saliva, and mouth-rinsed water

• Published in: Scientific reports Vol. 12; no. 1; pp. 689 - 9
• Main Authors: Maruyama, Yuki, Nishimoto, Yuichiro, Umezawa, Kouta, Kawamata, Ryosuke, Ichiba, Yuko, Tsutsumi, Kota, Kimura, Mitsuo, Murakami, Shinnosuke, Kakizawa, Yasushi, Kumagai, Takashi, Yamada, Takuji, Fukuda, Shinji
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.01.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/61/320; 639/638/11/296; 692/698/3008/3014; Adult; Capillary electrophoresis; Electrophoresis, Capillary; Female; Healthy Volunteers; Humanities and Social Sciences; Humans; Male; Mass Spectrometry; Mass spectroscopy; Metabolites; Metabolome; Metabolomics - methods; Mouth; Mouth - metabolism; Mouthwashes - analysis; multidisciplinary; Saliva; Saliva - metabolism; Sampling methods; Science; Science (multidisciplinary); Young Adult

Saliva includes a substantial amount of biological information, which has enabled us to understand the relationship between oral metabolites and various oral and systemic disorders. However, collecting saliva using a controlled protocol is time-consuming, making saliva an unsuitable analyte in large...