Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia - Wang, Yuanyuan; Bai, Changsen; Ruan, Yuxia; Liu, Miao; Chu, Qiaoyun; Qiu, Li; Yang, Chuanzhen; Li, Binghui (Nature communications, 2019)
Keywords: 631/45/320; 631/67/2327; Acetyl Coenzyme A - metabolism; Ammonia; Ammonia - metabolism; Ammonia - toxicity; Animals; Biosynthesis; Cancer; Carbon; Carbon - chemistry; Carbon - metabolism; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Coenzyme A; Female; Glucose - metabolism; Glutamine; Glutamine - chemistry; Glutamine - metabolism; HEK293 Cells; Humanities and Social Sciences; Humans; Hypoxia; Lactic acid; Lactic Acid - metabolism; Lipogenesis; Metabolic flux; Metabolic Networks and Pathways; Metabolism; Metabolome; Metabolomics; Mice; Mice, Nude; multidisciplinary; Neoplasms - blood; Neoplasms - metabolism; Neoplasms - mortality; Neoplasms - pathology; Nitrogen; Nitrogen - chemistry; Nitrogen - metabolism; Nucleotides - biosynthesis; Orotic Acid - analogs & derivatives; Orotic Acid - metabolism; Science; Science (multidisciplinary); Tumor Microenvironment; Uridine; Xenograft Model Antitumor Assays