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Abstract Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs. The existence of a relationship between migraine and sleep disorders has been recognized from centuries by clinicians and epidemiological studies. Nevertheless, the exact nature of this association, the underlying mechanisms and interactions are complex and not completely understood. Recent biochemical and functional imaging studies identified central nervous system structures and neurotransmitters involved in the pathophysiology of migraine and also important for the regulation of normal sleep architecture, suggesting a possible causative role, in the pathogenesis of both disorders, of a dysregulation in these common nervous system pathways. This systematic review summarizes the existing data on migraine and sleep disorders with the aim to evaluate the existence of a causal relationship and to assess the presence of influencing factors. The identification of specific sleep disorders associated with migraine should induce clinicians to systematically assess their presence in migraine patients and to adopt combined treatment strategies.
AbstractList Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs. The existence of a relationship between migraine and sleep disorders has been recognized from centuries by clinicians and epidemiological studies. Nevertheless, the exact nature of this association, the underlying mechanisms and interactions are complex and not completely understood. Recent biochemical and functional imaging studies identified central nervous system structures and neurotransmitters involved in the pathophysiology of migraine and also important for the regulation of normal sleep architecture, suggesting a possible causative role, in the pathogenesis of both disorders, of a dysregulation in these common nervous system pathways. This systematic review summarizes the existing data on migraine and sleep disorders with the aim to evaluate the existence of a causal relationship and to assess the presence of influencing factors. The identification of specific sleep disorders associated with migraine should induce clinicians to systematically assess their presence in migraine patients and to adopt combined treatment strategies.
Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs.The existence of a relationship between migraine and sleep disorders has been recognized from centuries by clinicians and epidemiological studies. Nevertheless, the exact nature of this association, the underlying mechanisms and interactions are complex and not completely understood. Recent biochemical and functional imaging studies identified central nervous system structures and neurotransmitters involved in the pathophysiology of migraine and also important for the regulation of normal sleep architecture, suggesting a possible causative role, in the pathogenesis of both disorders, of a dysregulation in these common nervous system pathways.This systematic review summarizes the existing data on migraine and sleep disorders with the aim to evaluate the existence of a causal relationship and to assess the presence of influencing factors. The identification of specific sleep disorders associated with migraine should induce clinicians to systematically assess their presence in migraine patients and to adopt combined treatment strategies.
Abstract Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs. The existence of a relationship between migraine and sleep disorders has been recognized from centuries by clinicians and epidemiological studies. Nevertheless, the exact nature of this association, the underlying mechanisms and interactions are complex and not completely understood. Recent biochemical and functional imaging studies identified central nervous system structures and neurotransmitters involved in the pathophysiology of migraine and also important for the regulation of normal sleep architecture, suggesting a possible causative role, in the pathogenesis of both disorders, of a dysregulation in these common nervous system pathways. This systematic review summarizes the existing data on migraine and sleep disorders with the aim to evaluate the existence of a causal relationship and to assess the presence of influencing factors. The identification of specific sleep disorders associated with migraine should induce clinicians to systematically assess their presence in migraine patients and to adopt combined treatment strategies.
Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs.The existence of a relationship between migraine and sleep disorders has been recognized from centuries by clinicians and epidemiological studies. Nevertheless, the exact nature of this association, the underlying mechanisms and interactions are complex and not completely understood. Recent biochemical and functional imaging studies identified central nervous system structures and neurotransmitters involved in the pathophysiology of migraine and also important for the regulation of normal sleep architecture, suggesting a possible causative role, in the pathogenesis of both disorders, of a dysregulation in these common nervous system pathways.This systematic review summarizes the existing data on migraine and sleep disorders with the aim to evaluate the existence of a causal relationship and to assess the presence of influencing factors. The identification of specific sleep disorders associated with migraine should induce clinicians to systematically assess their presence in migraine patients and to adopt combined treatment strategies.Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs.The existence of a relationship between migraine and sleep disorders has been recognized from centuries by clinicians and epidemiological studies. Nevertheless, the exact nature of this association, the underlying mechanisms and interactions are complex and not completely understood. Recent biochemical and functional imaging studies identified central nervous system structures and neurotransmitters involved in the pathophysiology of migraine and also important for the regulation of normal sleep architecture, suggesting a possible causative role, in the pathogenesis of both disorders, of a dysregulation in these common nervous system pathways.This systematic review summarizes the existing data on migraine and sleep disorders with the aim to evaluate the existence of a causal relationship and to assess the presence of influencing factors. The identification of specific sleep disorders associated with migraine should induce clinicians to systematically assess their presence in migraine patients and to adopt combined treatment strategies.
ArticleNumber 126
Author Martelletti, Paolo
Piroso, Serena
Glazyrina, Tatyana
Sacco, Simona
Tiseo, Cindy
Filimonova, Tamara
Vacca, Alessandro
Felbush, Anton
Overeem, Lucas Hendrik
Hubalek, Irina Anna
Gai, Annalisa
Marchenko, Yelena
Tkachev, Alexander
Author_xml – sequence: 1
  givenname: Cindy
  surname: Tiseo
  fullname: Tiseo, Cindy
  organization: Department of Applied Clinical Sciences and Biotechnology, University of L’Aquila, Regional Referral Headache Centre, S.S. Filippo e Nicola Hospital
– sequence: 2
  givenname: Alessandro
  surname: Vacca
  fullname: Vacca, Alessandro
  organization: Headache Center, Department of Neuroscience “Rita Levi Montalcini”, University of Torino
– sequence: 3
  givenname: Anton
  surname: Felbush
  fullname: Felbush, Anton
  organization: Pain Treatment Center, OOO “Vertebra”
– sequence: 4
  givenname: Tamara
  surname: Filimonova
  fullname: Filimonova, Tamara
  organization: Federal State Budget Educational Institution of Higher Education “Academician Ye. A. Vagner Perm State Medical University” of the Ministry of Healthcare of the Russian Federation
– sequence: 5
  givenname: Annalisa
  surname: Gai
  fullname: Gai, Annalisa
  organization: Headache Center, Department of Neuroscience “Rita Levi Montalcini”, University of Torino
– sequence: 6
  givenname: Tatyana
  surname: Glazyrina
  fullname: Glazyrina, Tatyana
  organization: LLC Stomat Business Company
– sequence: 7
  givenname: Irina Anna
  surname: Hubalek
  fullname: Hubalek, Irina Anna
  organization: Department of Neurology, Headache Center, Charité University Medicine Berlin
– sequence: 8
  givenname: Yelena
  surname: Marchenko
  fullname: Marchenko, Yelena
  organization: V. A. Almazov National Medical Research Centre
– sequence: 9
  givenname: Lucas Hendrik
  surname: Overeem
  fullname: Overeem, Lucas Hendrik
  organization: Charité – Universitätsmedizin Berlin Charité Centrum Neurologie, Neurochirurgie und Psychiatrie CC
– sequence: 10
  givenname: Serena
  surname: Piroso
  fullname: Piroso, Serena
  organization: Department of Human Neurosciences, Sapienza University of Rome
– sequence: 11
  givenname: Alexander
  surname: Tkachev
  fullname: Tkachev, Alexander
  organization: Department of Neurology, Neurosurgery, medical genetics, I.M. Sechenov First Moscow State Medical University
– sequence: 12
  givenname: Paolo
  surname: Martelletti
  fullname: Martelletti, Paolo
  organization: Department of Clinical and Molecular Medicine, Sapienza University of Rome, Regional Referral Headache Centre, Sant’Andrea Hospital
– sequence: 13
  givenname: Simona
  orcidid: 0000-0003-0651-1939
  surname: Sacco
  fullname: Sacco, Simona
  email: simona.sacco@yahoo.com
  organization: Department of Applied Clinical Sciences and Biotechnology, University of L’Aquila, Regional Referral Headache Centre, S.S. Filippo e Nicola Hospital
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33109076$$D View this record in MEDLINE/PubMed
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– notice: The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
CorporateAuthor on behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)
European Headache Federation School of Advanced Studies (EHF-SAS)
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Issue 1
Keywords Headache
Sleep disorders
Circadian rhythm sleep-wake disorders
Insomnia
Migraine
Periodic limb movement disorder
Restless leg syndrome
Narcolepsy
Sleep apnea
Parasomnias
Language English
License Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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PublicationSubtitle Official Journal of the "European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"
PublicationTitle Journal of headache and pain
PublicationTitleAbbrev J Headache Pain
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PublicationYear 2020
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Snippet Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable...
Abstract Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with...
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StartPage 126
SubjectTerms Central nervous system
Circadian rhythm
Epidemiology
Headache
Humans
Insomnia
Internal Medicine
Medicine
Medicine & Public Health
Migraine
Migraine Disorders - complications
Migraine Disorders - epidemiology
Narcolepsy
Nervous system
Neurology
Neurotransmitters
Pain Medicine
Restless leg syndrome
Review
Review Article
Sleep
Sleep apnea
Sleep disorders
Sleep Wake Disorders - complications
Sleep Wake Disorders - epidemiology
Systematic review
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Title Migraine and sleep disorders: a systematic review
URI https://link.springer.com/article/10.1186/s10194-020-01192-5
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Volume 21
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